Long COVID: A Dysregulated Immune Response Could Explain Symptoms Persistence

Covid-19: Intracellular observation of reconstituted human respiratory epithelium MucilAir(TM) infected with SARS-CoV-2. Manuel Rosa-Calatrava, Inserm; Olivier Terrier, CNRS; Andrés Pizzorno, Signia Therapeutics; Elisabeth Errazuriz-Cerda UCBL1 CIQLE. VirPath (International Research Center in Infectiology U1111 Inserm - UMR 5308 CNRS - ENS Lyon - UCBL1). Colorized by Noa Rosa C. Several months after SARS-CoV-2 infection, some patients continue to have symptoms. This phenomenon, known as "post-COVID condition” or, more commonly, "long COVID”, remains poorly documented. In order to address this and improve patient care, research teams are trying to improve their understanding of the underlying biological and immunological mechanisms. In a new study, scientists from Inserm and Université de Montpellier at the Montpellier Cancer Research Institute, in collaboration with Montpellier University Hospital , have highlighted the possible role of the dysregulation of a part of the innate immune defense.