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Health - Pharmacology - 23.05.2023 
A marine worm, life saver
In 2020, in the midst of the COVID-19 crisis, we spoke with Franck Zal, a doctor in marine biology from Sorbonne University and founder of the company Hemarina. At the time, HEMO2life - their flagship product created from the hemoglobin of the marine worm, the arenicole - was envisaged to improve the oxygenation of patients suffering from acute respiratory distress syndrome.
Life Sciences - Health - 22.05.2023 
Liver cells control our biological clock
The liver could influence the body's central biological clock, a group of brain cells that influence most aspects of physiology and behaviour. Our liver plays a role in regulating our central biological clock, scientists from CNRS and Université Paris have discovered. The results of their study, published on 17 May in Science Advances, show that the biological clock of mice can be reprogrammed by inserting human liver cells into the animal's liver.
Life Sciences - Health - 22.05.2023 
Liver cells control our biological clock
The liver may influence the body's central biological clock, a group of brain cells that influence most physiological and behavioral aspects. Our liver partly controls our central biological clock, according to scientists from CNRS and Université Paris Cité. Their study, to be published on May 17, 2023 in the journal Science Advances, has indeed shown that it was possible to shift the biological clock of mice by introducing human liver cells into their liver.
Health - Chemistry - 16.05.2023 
New molecule to target and eradicate cancer cells with light
Scientists have designed a molecule that can accumulate in cancer cells specifically and become toxic upon exposure to light. Scientists from the CNRS, ENS de Lyon, University of Angers, and Claude Bernard Lyon 1 University, in collaboration with colleagues from Swedish and South Korean institutions, have developed a new molecule that selectively accumulates in cancer cells and, after exposure to light, turns toxic.
Life Sciences - Health - 10.05.2023
Health - Computer Science - 05.05.2023 
An automated computer assistant specialized in the diagnosis of transplant rejection
In a recent study published in the journal Nature Medicine , a research team from Université Paris Cité, Inserm and AP-HP, led by Professor Alexandre Loupy at the Centre d'expertise de la transplantation multi-organ de Paris, has created an automated computer assistant that can correct 40% of misdiagnoses of allograft rejection in humans and better guide patient management .
Health - Computer Science - 04.05.2023 
AI: A new French algorithm inspired by GPT improves trauma surveillance
In France, one third of emergency room visits are due to trauma. In order to better understand their mechanisms and improve their management, researchers from Inserm and the University of Bordeaux at the Bordeaux Population Health research center, together with teams from the Bordeaux University Hospital, have developed an algorithm capable of classifying emergency room visits due to trauma by analyzing clinical reports through artificial intelligence (GPT).
Health - Life Sciences - 03.05.2023
Health - Chemistry - 26.04.2023 
Inflammation and cancer: identifying the role of copper paves the way for new therapeutic applications
For the first time, researchers from Institut Curie, the CNRS and Inserm have uncovered a previously unknown chain of biochemical reactions. This chain involves copper and leads to metabolic and epigenetic alterations that activate inflammation and tumorigenesis. But there is more; the research team developed a "drug prototype" capable of mitigating both the mechanisms of inflammation and the processes potentially involved in metastatic spread.
Health - Environment - 24.04.2023
Health - Life Sciences - 18.04.2023
Health - Pharmacology - 11.04.2023
Life Sciences - Health - 03.04.2023
Health - Life Sciences - 27.03.2023
Health - Pharmacology - 23.03.2023
Health - Life Sciences - 23.03.2023
Health - Pharmacology - 21.03.2023
Health - Transport - 20.03.2023 
Using Modeling to Limit Infectious Disease Transmission at Airports and Train Stations
In crowded places, such as airports and train stations, social distancing is difficult to maintain and the risk of infectious disease transmission is increased. In order to reduce this risk, it is essential that we improve our understanding of the dynamics of disease transmission within such places and the effective mitigation measures that can be implemented at low cost.
Health - Environment - 17.03.2023
Health - Pharmacology - 14.03.2023
Health
Results 1 - 20 of 270.
In 2020, in the midst of the COVID-19 crisis, we spoke with Franck Zal, a doctor in marine biology from Sorbonne University and founder of the company Hemarina. At the time, HEMO2life - their flagship product created from the hemoglobin of the marine worm, the arenicole - was envisaged to improve the oxygenation of patients suffering from acute respiratory distress syndrome.
The liver could influence the body's central biological clock, a group of brain cells that influence most aspects of physiology and behaviour. Our liver plays a role in regulating our central biological clock, scientists from CNRS and Université Paris have discovered. The results of their study, published on 17 May in Science Advances, show that the biological clock of mice can be reprogrammed by inserting human liver cells into the animal's liver.
The liver may influence the body's central biological clock, a group of brain cells that influence most physiological and behavioral aspects. Our liver partly controls our central biological clock, according to scientists from CNRS and Université Paris Cité. Their study, to be published on May 17, 2023 in the journal Science Advances, has indeed shown that it was possible to shift the biological clock of mice by introducing human liver cells into their liver.
Scientists have designed a molecule that can accumulate in cancer cells specifically and become toxic upon exposure to light. Scientists from the CNRS, ENS de Lyon, University of Angers, and Claude Bernard Lyon 1 University, in collaboration with colleagues from Swedish and South Korean institutions, have developed a new molecule that selectively accumulates in cancer cells and, after exposure to light, turns toxic.
Seeing with Sound
Restoring sight to blind people thanks to a therapy that combines genetics and ultrasound is the hope of Serge Picaud's team, director of the Vision Institute *, and the Physics for Medicine Laboratory of the ESPCI ** in partnership with the Institute of Molecular and Clinical Ophthalmology of Basel.
Restoring sight to blind people thanks to a therapy that combines genetics and ultrasound is the hope of Serge Picaud's team, director of the Vision Institute *, and the Physics for Medicine Laboratory of the ESPCI ** in partnership with the Institute of Molecular and Clinical Ophthalmology of Basel.
In a recent study published in the journal Nature Medicine , a research team from Université Paris Cité, Inserm and AP-HP, led by Professor Alexandre Loupy at the Centre d'expertise de la transplantation multi-organ de Paris, has created an automated computer assistant that can correct 40% of misdiagnoses of allograft rejection in humans and better guide patient management .
In France, one third of emergency room visits are due to trauma. In order to better understand their mechanisms and improve their management, researchers from Inserm and the University of Bordeaux at the Bordeaux Population Health research center, together with teams from the Bordeaux University Hospital, have developed an algorithm capable of classifying emergency room visits due to trauma by analyzing clinical reports through artificial intelligence (GPT).
Long COVID: The Persistence of SARS-CoV-2 in the Mucous Membranes May Be A Factor
This transmission electron microscope image shows SARS-CoV-2, isolated from a patient in the U.S., emerging from the surface of cells cultivated in a laboratory. National Institute of Allergy and Infectious Diseases-Rocky Mountain Laboratories, NIH. Public domain. Several months after infection with SARS-CoV-2, some patients still have symptoms: a phenomenon commonly referred to as "long COVID”.
This transmission electron microscope image shows SARS-CoV-2, isolated from a patient in the U.S., emerging from the surface of cells cultivated in a laboratory. National Institute of Allergy and Infectious Diseases-Rocky Mountain Laboratories, NIH. Public domain. Several months after infection with SARS-CoV-2, some patients still have symptoms: a phenomenon commonly referred to as "long COVID”.
For the first time, researchers from Institut Curie, the CNRS and Inserm have uncovered a previously unknown chain of biochemical reactions. This chain involves copper and leads to metabolic and epigenetic alterations that activate inflammation and tumorigenesis. But there is more; the research team developed a "drug prototype" capable of mitigating both the mechanisms of inflammation and the processes potentially involved in metastatic spread.
Hypertension: A Mixture of Air Pollutants Could Cause Repeated High Blood Pressure Peaks
Air pollution is an acknowledged environmental factor in high blood pressure. It consists of a mixture of particles and gases whose combined effects on human health are not yet well known. A team from Inserm and Sorbonne Université, assisted by international collaborators, used continuous monitoring to study the daily life impact of a mixture of five air pollutants on the blood pressure of 221 MobiliSense study participants in the Greater Paris area.
Air pollution is an acknowledged environmental factor in high blood pressure. It consists of a mixture of particles and gases whose combined effects on human health are not yet well known. A team from Inserm and Sorbonne Université, assisted by international collaborators, used continuous monitoring to study the daily life impact of a mixture of five air pollutants on the blood pressure of 221 MobiliSense study participants in the Greater Paris area.
A sponsorship from Quercia Venture Management in support of obesity research
An innovative research program on the theme of "Nutrition and Obesity: Systemic Approaches", led by Professor Karine Clément and her team, benefits from the sponsorship of Quercia Venture Management. We are currently experiencing a global epidemic of obesity resulting from the interactions between our genetic heritage and numerous environmental factors.
An innovative research program on the theme of "Nutrition and Obesity: Systemic Approaches", led by Professor Karine Clément and her team, benefits from the sponsorship of Quercia Venture Management. We are currently experiencing a global epidemic of obesity resulting from the interactions between our genetic heritage and numerous environmental factors.
A New Target to Regress Liver Fibrosis
Cirrhosis is the final stage of fibrosis associated with chronic liver diseases. It affects 200,000 to 500,000 individuals in France and is responsible for 170,000 deaths per year in Europe. Adobe Stock Chronic liver diseases are characterized by persistent inflammation that contributes to their progression to more severe stages.
Cirrhosis is the final stage of fibrosis associated with chronic liver diseases. It affects 200,000 to 500,000 individuals in France and is responsible for 170,000 deaths per year in Europe. Adobe Stock Chronic liver diseases are characterized by persistent inflammation that contributes to their progression to more severe stages.
Restoring Vision Through a New Brain-Machine Interface: Sonogenetic Therapy
Sonogenetic therapy consists of genetically modifying certain neurons in order to activate them remotely by ultrasound. © Alexandre Dizeux/Physics for Medicine Paris Restore vision using a combination of ultrasound and genetics? This is the goal of an international team led by Inserm research directors Mickael Tanter and Serge Picaud from Paris' Physics for Medicine unit (ESPCI Paris/PSL Université/Inserm/CNRS) and Vision Institute (Sorbonne Université/Inserm/CNRS), respectively, in partnership with the Institute of Molecular and Clinical Ophthalmology in Basel.
Sonogenetic therapy consists of genetically modifying certain neurons in order to activate them remotely by ultrasound. © Alexandre Dizeux/Physics for Medicine Paris Restore vision using a combination of ultrasound and genetics? This is the goal of an international team led by Inserm research directors Mickael Tanter and Serge Picaud from Paris' Physics for Medicine unit (ESPCI Paris/PSL Université/Inserm/CNRS) and Vision Institute (Sorbonne Université/Inserm/CNRS), respectively, in partnership with the Institute of Molecular and Clinical Ophthalmology in Basel.
Towards a Better Understanding of the Role of Male Hormones in Women with Multiple Sclerosis
The image shows the brain region where demyelination is typically induced. The red cells correspond to all of the microglial cells with inflammatory properties when demyelination has just occurred. If the spontaneous regeneration process of myelin is effective, their inflammatory nature then diminishes in favor of an anti-inflammatory and pro-regenerative nature.
The image shows the brain region where demyelination is typically induced. The red cells correspond to all of the microglial cells with inflammatory properties when demyelination has just occurred. If the spontaneous regeneration process of myelin is effective, their inflammatory nature then diminishes in favor of an anti-inflammatory and pro-regenerative nature.
Covid-19: infection-vaccination combination best protects against reinfection with SARS-CoV-2
Publication of the CIRI in the journal Science Translational Medicine on March 15, 2023. Press realease of the INSERM on March 17, 2023. A large proportion of the population has developed immunity to SARS-CoV-2 following infection and/or vaccination. In addition, some infected patients benefit from a so-called "hybrid" immunity when they have been vaccinated after their infectious episode.
Publication of the CIRI in the journal Science Translational Medicine on March 15, 2023. Press realease of the INSERM on March 17, 2023. A large proportion of the population has developed immunity to SARS-CoV-2 following infection and/or vaccination. In addition, some infected patients benefit from a so-called "hybrid" immunity when they have been vaccinated after their infectious episode.
Alzheimer’s disease: new contrast agents
Publication of the Chemistry Laboratory in the journal Nanomedicine on March 17, 2023. Communication of the CNRS-INC on March 20, 2023. A consortium of European researchers led by two Lyon laboratories - the Chemistry Laboratory (CNRS/ENS de Lyon/Université Claude Bernard Lyon 1) and the Lyon Neuroscience Research Center ( CNRS/Claude Bernard Lyon 1 university/Jean Monnet University/Inserm) - is proposing a new "multi-technique" imaging agent (MRI, X-ray, fluorescence..) targeting amyloid-? (A?) plaques, the first pathological signs of Alzheimer's disease (AD).
Publication of the Chemistry Laboratory in the journal Nanomedicine on March 17, 2023. Communication of the CNRS-INC on March 20, 2023. A consortium of European researchers led by two Lyon laboratories - the Chemistry Laboratory (CNRS/ENS de Lyon/Université Claude Bernard Lyon 1) and the Lyon Neuroscience Research Center ( CNRS/Claude Bernard Lyon 1 university/Jean Monnet University/Inserm) - is proposing a new "multi-technique" imaging agent (MRI, X-ray, fluorescence..) targeting amyloid-? (A?) plaques, the first pathological signs of Alzheimer's disease (AD).
COVID-19: Infection-Vaccination is the Most Protective Combination Against Reinfection
A large part of the population has developed immunity against SARS-CoV-2 following infection, vaccination - or both. In addition, some infected patients enjoy "hybrid” immunity when they are vaccinated following their infectious episode. Scientists from Inserm, CNRS, Université Claude-Bernard Lyon 1 and ENS de Lyon at the International Center for Research on Infectious Diseases (CIRI) seek to characterize the imprint left by SARS-CoV-2 exposure through vaccination or the combination of the two events on immune memory.
A large part of the population has developed immunity against SARS-CoV-2 following infection, vaccination - or both. In addition, some infected patients enjoy "hybrid” immunity when they are vaccinated following their infectious episode. Scientists from Inserm, CNRS, Université Claude-Bernard Lyon 1 and ENS de Lyon at the International Center for Research on Infectious Diseases (CIRI) seek to characterize the imprint left by SARS-CoV-2 exposure through vaccination or the combination of the two events on immune memory.
In crowded places, such as airports and train stations, social distancing is difficult to maintain and the risk of infectious disease transmission is increased. In order to reduce this risk, it is essential that we improve our understanding of the dynamics of disease transmission within such places and the effective mitigation measures that can be implemented at low cost.
Extreme Temperatures During Pregnancy: A Possible Impact on the Lung Development of Newborn Girls
Exposure to extreme temperatures from the fetal stage could impact health. This is what suggests a study by researchers from Inserm, Université Grenoble Alpes and CNRS, based on the SEPAGES cohort , intended to study the impact of various environmental factors on the health of pregnant women and their children.
Exposure to extreme temperatures from the fetal stage could impact health. This is what suggests a study by researchers from Inserm, Université Grenoble Alpes and CNRS, based on the SEPAGES cohort , intended to study the impact of various environmental factors on the health of pregnant women and their children.
Pancreatic cancer: discovery of a molecular test allows for personalized treatment
Inserm researchers at the Marseille Cancer Research Center (CRCM - AMU/Inserm/CNRS/IPC) and clinicians at the Paoli-Calmettes Institute (IPC) have identified a molecular test for personalized treatment of pancreatic cancer. This new strategy, based on the prediction of the sensitivity of each patient to the different chemotherapy protocols currently available, opens the way to personalized treatments for pancreatic cancer.
Inserm researchers at the Marseille Cancer Research Center (CRCM - AMU/Inserm/CNRS/IPC) and clinicians at the Paoli-Calmettes Institute (IPC) have identified a molecular test for personalized treatment of pancreatic cancer. This new strategy, based on the prediction of the sensitivity of each patient to the different chemotherapy protocols currently available, opens the way to personalized treatments for pancreatic cancer.
