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Life Sciences - Health - 22.11.2016
The cause of uncombable hair syndrome identified
In 1973, the rare syndrome of uncombable hair or - pili trianguli et canaliculi - was described by a Toulouse dermatologist. More than 40 years later, Michel Simon, Inserm research director his colleagues at the 'Epidermal Differentiation and Rheumatoid Autoimmunity' Unit [UDEAR] (Inserm/CNRS/Toulouse III - Paul Sabatier University) have identified its genetic cause.

Health - Life Sciences - 21.11.2016
Functional human intestine grown from stem cells
American researchers at the Cincinnati Children's Hospital Medical Center and French researchers from Inserm (joint research Unit 913 'Neuropathies of Enteric Nervous System and Digestive Diseases', Nantes) have succeeded in generating a functional human intestine using pluripotent human stem cells.

Life Sciences - Health - 21.11.2016
Mitochondria are essential to memory
Numerous studies have shown that using cannabis can lead to shortand long-term memory loss. These effects on memory may be related to the presence of specific receptors on several types of brain cells (glial cells as well as neurons). Inserm researchers led by Giovanni Marsicano (Neurocentre Magendie, U1215) have shown that these effects on memory are related to the presence of these same receptors on the mitochondria, the energy centre of the cell.

Health - Agronomy / Food Science - 17.11.2016
Nutritional prevention a possible method to limit risk of cancers linked to iron in meat products
Nutritional prevention a possible method to limit risk of cancers linked to iron in meat products
Recent data suggests that the consumption of nutritional iron could be linked to a high risk of breast cancer, and a diet rich in antioxidants appears to be effective at limiting this risk. Such are the findings of a study led by INRA and INSERM 1 researchers, published in the journal Oncotarget . These new results confirm those found in animals AND findings on colon cancer.

Physics - Health - 03.11.2016
France doubles its experimental capability in nuclear physics
France doubles its experimental capability in nuclear physics
The new SPIRAL2 particle accelerator at the French large heavy-ion accelerator GANIL (CNRS/CEA), inaugurated on November 3 in the presence of the French President François Hollande, will be able to p

Health - 25.10.2016
The French are overweight - confirmed by the Constances cohort
Nearly one in two French people over 30 years of age are overweight. This is what the first results from the Constances cohort has revealed. Now supported by Inserm and the French national social security organisation for salaries workers (Cnamts), Constances collates health data on more than 110,000 French people.

Agronomy / Food Science - Health - 24.10.2016
Cutting down on salt, fat and sugar in diets
Cutting down on salt, fat and sugar in diets
Cheese, chorizo, dry sausages, muffins, madeleines, custards and pizza sauce: for four years, these foods have been getting a makeover with the INRA-coordinated European project TeRiFiQ.

Health - 07.10.2016
Rituximab effective in the treatment of membranous glomerulonephritis
A national trial on membranous glomerulonephritis in 80 patients was coordinated by Prof. Pierre Ronco, of the Department of Nephrology and Dialysis at Tenon Hospital AP-HP, of the Inserm Unit 'Rare and common kidney diseases, matrix remodelling and tissue repair' and Pierre and Marie Curie University, and by Dr Karine Dahan, of the Nephrology Day Hospital at Tenon Hospital AP-HP.

Health - 06.10.2016
New immunotherapy-based approach for post-transplant leukaemia relapse
An Inserm team from the Mondor Institute for Biomedical Research (IMRB) has just identified a key switch in the immune response, and proposes a new immunotherapy-based approach for combating leukaemia. And maybe other cancers in time. This work is published in the journal Blood . Towards a new immunotherapy for cancer?

Life Sciences - Health - 05.10.2016
Eating well to grow well: discovery of a missing link
Rénald Delanoue, Inserm Researcher, and his colleagues at the Institute of Biology Valrose in Nice (Inserm-CNRS-Université Côte d'Azur) have identified the missing links in the process that regulates the size of an organism based on the richness of its diet. Their research was conducted on Drosophila , an insect that seems very distant from humans, but the study of which has nonetheless enabled many advances in biomedical research.

Life Sciences - Health - 04.10.2016
Invasive insects: an underestimated cost to the world economy
Invasive insects: an underestimated cost to the world economy
Invasive insects cause at least 69 billion euros of damage per annum worldwide.

Life Sciences - Health - 12.09.2016
Low birth rate after cloning: the consequences of highly disruptive interactions between uterus and embryo
Low birth rate after cloning: the consequences of highly disruptive interactions between uterus and embryo
When comparing cloned animal embryos and embryos that come about as a result of artificial insemination, there is a difference in gene expression at the moment implantation occurs in the uterus for more than 5 000 genes. Researchers at INRA and the University of California are shining the spotlight on this critical step for the survival of cloned embryos in cattle.

Life Sciences - Health - 12.09.2016
Low birth rate after cloning: the consequences of highly disruptive interactions between uterus and embryo
Low birth rate after cloning: the consequences of highly disruptive interactions between uterus and embryo
When comparing cloned animal embryos and embryos that come about as a result of artificial insemination, there is a difference in gene expression at the moment implantation occurs in the uterus for more than 5 000 genes. Researchers at INRA and the University of California are shining the spotlight on this critical step for the survival of cloned embryos in cattle.

Life Sciences - Health - 02.09.2016
Placenta in females, muscle mass in males: the dual heritage of a virus
Placenta in females, muscle mass in males: the dual heritage of a virus
It was already known that genes inherited from ancient retroviruses 1 are essential to the placenta in mammals, a finding to which scientists in the Laboratoire Physiologie et Pathologie Moléculaires des Rétrovirus Endogènes et Infectieux (CNRS/Université Paris-Sud) contributed. Today, the same scientists 2 have revealed a new chapter in this astonishing story: these genes of viral origin may also be responsible for the more developed muscle mass seen in males! Their findings are published on 2 September 2016 in PLOS Genetics .

Life Sciences - Health - 30.08.2016
Caffeine reverts memory deficits
Caffeine reverts memory deficits
The mechanism by which caffeine counteracts age-related cognitive deficits in animals has been revealed. The study coordinated by Portuguese researchers from Instituto de Medicina Molecular (iMM Lisboa) and collaborators from Inserm in Lille, France, along with teams from Germany and United States, showed that the abnormal expression of a particular receptor - the adenosine A2A, target for caffeine - in the brain of rats induces an aging-like profile namely memory impairments linked to the loss of stress controlling mechanisms.

Health - Life Sciences - 05.08.2016
Malaria and toxoplasmosis have an Achilles heel from plants
Malaria and toxoplasmosis have an Achilles heel from plants
To survive, the parasites responsible for malaria and toxoplasmosis depend on mechanisms inherited from the plant world. This is what a team of researchers from CNRS 1 (Institute for Advanced Biosciences, CNRS/INSERM/Université Grenoble Alpes) and the University of Melbourne 2 has shown. They have just published two studies in Cell Microbiology and PLOS Pathogens.

Life Sciences - Health - 03.08.2016
The keys to a major process in DNA repair
Researchers from the Institut Jacques Monod (CNRS/University of Paris Diderot), the Institute of Biology of the Ecole Normale Supérieure (ENS/CNRS/Inserm), and the University of Bristol, have described for the first time in its totality the mechanisms by which DNA damaged by UV radiation is repaired, and how the proteins involved in this process cooperate to ensure its efficiency.

Life Sciences - Health - 29.07.2016
A virtual brain helps decrypt epilepsy
Researchers at CNRS, INSERM, Aix-Marseille University and AP-HM have just created a virtual brain that can reconstitute the brain of a person affected by epilepsy for the first time. From this work we understand better how the disease works and can also better prepare for surgery. These results are published in Neuroimage, on July 28, 2016.

Health - Life Sciences - 29.07.2016
A virtual brain helps decrypt epilepsy
A virtual brain helps decrypt epilepsy
Researchers at CNRS, INSERM, Aix-Marseille University and AP-HM have just created a virtual brain that can reconstitute the brain of a person affected by epilepsy for the first time. From this work we understand better how the disease works and can also better prepare for surgery. These results are published in Neuroimage, on July 28, 2016.

Health - Administration - 27.07.2016
Inserm, France’s rising research star according to Nature
The French National Institute of Health and Medical Research (Inserm) is the only research institution in France listed in the World Top 100 institutions with the most progress in the last 3 years.
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