Questioning the link between pollution by magnetite particles and Alzheimer’s disease

A 2016 study ¹ showed that exposure to urban pollution involving magnetite particles played a role in the development of Alzheimer's disease. It began from the hypothesis that magnetite particles would generate chemical reactions that could cause oxidative stress for neurons. CNRS researchers have now called this connection into question, showing that it is very unlikely that magnetite is involved in neuron degeneration. Their work was published in Angewandte Chemie International Edition on October 11, 2018. Magnetite, which is one of the main iron ores, is very stable, even over the geological timescale. However, a scientific study that appeared in 2016 suggested that magnetite nanoparticles coming from atmospheric pollution could penetrate the brain by inhalation and, by binding to amyloid peptide ² , cause the neuron degeneration responsible for Alzheimer's disease. A 2007 study ³ described that magnetite could generate harmful oxidation reactions.