New therapeutic prospect for preeclampsia

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Placental cells are stained blue (nuclei) and the reactive oxygen species produc
Placental cells are stained blue (nuclei) and the reactive oxygen species produced by mitochondria are stained red by fluorescence. The levels of these reactive species are altered during preeclampsia. © Laurent Chatre, Institut Pasteur/CNRS
Placental cells are stained blue (nuclei) and the reactive oxygen species produced by mitochondria are stained red by fluorescence. The levels of these reactive species are altered during preeclampsia. Laurent Chatre, Institut Pasteur/CNRS - Preeclampsia is a condition that affects the placenta during pregnancy and is dangerous for both the fetus and the mother. Scientists from the Institut Pasteur, Inserm and the CNRS have proposed a new therapy, tested in two rodent models, that corrects the defects identified in placental cells, and restores placental and fetal weight. The treatment successfully lowers blood pressure in the mother and resolves the characteristic preeclampsia symptoms of excess protein in urine and cardiovascular abnormalities. The research was published on July xx in the journal Redox Biology . Preeclampsia is a placental dysfunction that affects approximately 2 to 8% of pregnant women worldwide.
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