The research team developed a ’drug prototype’ capable of mitigating both the mechanisms of inflammation and the processes potentially involved in metastatic spread.
The research team developed a 'drug prototype' capable of mitigating both the mechanisms of inflammation and the processes potentially involved in metastatic spread. Institut Curie / BELONCLE Frank - For the first time, researchers from Institut Curie, the CNRS and Inserm have uncovered a previously unknown chain of biochemical reactions. This chain involves copper and leads to metabolic and epigenetic alterations that activate inflammation and tumorigenesis. But there is more; the research team developed a "drug prototype" capable of mitigating both the mechanisms of inflammation and the processes potentially involved in metastatic spread. Published in the journal Nature on April 26, 2023, these results provide hope for new therapeutic opportunities to control inflammation and cancer. Inflammation is a complex biological process that can eradicate pathogens and promotes repair of damaged tissues. However, deregulation of the immune system can lead to uncontrolled inflammation and produce lesions instead.
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