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Health - Pharmacology - 23.03.2023
Covid-19: infection-vaccination combination best protects against reinfection with SARS-CoV-2
Publication of the CIRI in the journal Science Translational Medicine on March 15, 2023. Press realease of the INSERM on March 17, 2023. A large proportion of the population has developed immunity to SARS-CoV-2 following infection and/or vaccination. In addition, some infected patients benefit from a so-called "hybrid" immunity when they have been vaccinated after their infectious episode.

Health - Life Sciences - 23.03.2023
Alzheimer’s disease: new contrast agents
Publication of the Chemistry Laboratory in the journal Nanomedicine on March 17, 2023. Communication of the CNRS-INC on March 20, 2023. A consortium of European researchers led by two Lyon laboratories - the Chemistry Laboratory (CNRS/ENS de Lyon/Université Claude Bernard Lyon 1) and the Lyon Neuroscience Research Center ( CNRS/Claude Bernard Lyon 1 university/Jean Monnet University/Inserm) - is proposing a new "multi-technique" imaging agent (MRI, X-ray, fluorescence..) targeting amyloid-? (A?) plaques, the first pathological signs of Alzheimer's disease (AD).

Life Sciences - Environment - 16.03.2023
Laure Bonnaud-Ponticelli: 'The octopus has phenomenal analytical capacities!'
Laure Bonnaud-Ponticelli: ’The octopus has phenomenal analytical capacities!’
Gone are the days when the octopus was, in the collective imagination, a frightening sea monster attacking Jules Verne's Nautilus. The image of the octopus has now changed. For example, the cephalopod took on the pseudonym Paul during the 2010 soccer World Cup, and made predictions about the outcomes of games (more or less successfully.

Life Sciences - Computer Science - 16.03.2023
Can artificial intelligence match how the brain processes sound ?
Without realising it, our brain continuously processes sounds and infers semantic information, such as the presence of birds in a tree based on hearing their song.

Materials Science - 15.03.2023
Notre Dame: First Gothic cathedral to make massive use of iron
Notre Dame: First Gothic cathedral to make massive use of iron
Study of metal components from Notre Dame site. Cyril FRESILLON / IRAMAT / NIMBE / ArScAn / CEA / Chantier Scientifique Notre-Dame de Paris / French Ministry of Culture / CNRS Is Notre Dame the original Iron Lady? Evidence of the earliest known use of the metal for the construction of a Gothic cathedral has been uncovered by a team of scientists 1 working at the Notre Dame research site (CNRS / French Ministry of Culture).

Health - Pharmacology - 14.03.2023
Pancreatic cancer: discovery of a molecular test allows for personalized treatment
Inserm researchers at the Marseille Cancer Research Center (CRCM - AMU/Inserm/CNRS/IPC) and clinicians at the Paoli-Calmettes Institute (IPC) have identified a molecular test for personalized treatment of pancreatic cancer. This new strategy, based on the prediction of the sensitivity of each patient to the different chemotherapy protocols currently available, opens the way to personalized treatments for pancreatic cancer.

Health - Pharmacology - 07.03.2023
A New Milestone in the Development of an Effective Allergic Asthma Vaccine
A New Milestone in the Development of an Effective Allergic Asthma Vaccine
To combat allergic asthma, which affects millions of people worldwide, scientists from Inserm, CNRS and Université Toulouse III-Paul Sabatier at the Infinity laboratory , Institut Pasteur and French company NEOVACS are developing and testing a new vaccine. In their previous study, the teams had shown it to be effective in producing antibodies capable of neutralizing human immune proteins that play a key role in triggering allergic asthma, cytokines IL-4 and IL-13.

Life Sciences - Health - 27.02.2023
Pre- and Postnatal Chlordecone Exposure Could Affect the Cognitive Development and Behavior of Children
Chlordecone is an organochlorine insecticide that was used in the French West Indies from 1973 to 1993 to control the banana root borer. Adobe Stock Despite the fact that chlordecone has not been used as an insecticide in the French West Indies for 30 years now, its persistence in the environment continues to contaminate the populations.

Health - Psychology - 23.02.2023
Cannabis: Insomnia Twice as Common Among Students Who Use It Every Day
The likelihood of suffering from insomnia was found to be 45% higher in cannabis users compared to non-users. In France, over half of students suffer from sleep complaints. These are particularly concerning as they can affect the success of their studies, and their physical and mental health. A real public health issue, the evaluation of these health risks is one of the research subjects of a team of scientists from Inserm, Université de Bordeaux and Bordeaux University Hospital.

Life Sciences - Health - 23.02.2023
How the microbiota stimulates growth
How the microbiota stimulates growth
1 While insulin-like growth factor 1 (IGF-1), mainly produced by the liver, has a chemical structure similar to that of insulin, these hormones have distinct functions: IGF-1 stimulates tissue and skeletal growth, whereas insulin regulates energy metabolism as required for growth. The gut microbiota is now thought to constitute an organ in its own right.

Life Sciences - Psychology - 21.02.2023
A blood factor involved in depression
A small group of neural stem cells isolated from mice and cultured in vitro observed under a confocal microscope. The process of aging is often related to the onset of cognitive decline, depression and memory loss. Scientists from the Institut Pasteur, CNRS and Inserm have discovered that administration of the GDF11 protein, which is known to regenerate murine neural stem cells, improves cognitive abilities and reduces the depressive state in aged mice.

Health - Pharmacology - 20.02.2023
Obesity and overweight: nearly one French person in two is affected
Obesity and overweight: nearly one French person in two is affected
Obesity is a global public health problem with an increasing incidence. According to the WHO, since 1975, the number of obesity cases has almost tripled worldwide . Obesity is associated with numerous comorbidities and high mortality. It is estimated that this complex chronic disease increases the risk of cardiovascular disease (first cause of death in the world), diabetes, musculoskeletal disorders, many forms of cancer (endometrial, breast, ovarian, prostate, liver, gallbladder, kidney and colon.

Health - Pharmacology - 17.02.2023
Better understand the transition from acute to chronic pain
Better understand the transition from acute to chronic pain
Researchers from the University of Montpellier and Inserm at the Montpellier Neuroscience Institute have shown the preponderant role of the FLT3 receptor in chronic post-surgical pain. By inhibiting this receptor with therapeutic antibodies, the scientists could propose promising avenues for the prevention of chronic pain.

Life Sciences - 13.02.2023
Who are the first ancestors of present-day fish?
Who are the first ancestors of present-day fish?
What is the origin of the ancestors of present-day fish? What species evolved from them? A 50-year-old scientific controversy revolved around the question of which group, the "bony-tongues” or the "eels”, was the oldest. A study by INRAE, the CNRS, the Pasteur Institute, Inserm and the Muséum National d'Histoire Naturelle , has just put an end to the debate by showing through genomic analysis that these fishes are in fact one and the same group, given the rather peculiar name of "Eloposteoglossocephala”.

Physics - 13.02.2023
Nuclear Fusion: A Historic Breakthrough
In December 2022, scientists at the National Ignition Facility (NIF) announced a "historic breakthrough" in the field of nuclear fusion. They succeeded, for the first time, in releasing more energy through fusion reactions than was necessary to cause them. Caterina Riconda, professor of physics at Sorbonne University in the Laboratory for the Use of Intense Lasers, and Pierre Morel, associate professor at the Laboratory of Plasma Physics, discuss these unprecedented results.

Chemistry - Physics - 10.02.2023
A new key discovery for tracing the origins of life
Publication of the LGL-TPE in the Journal of Physical Chemistry A on January 11, 2023. Press realease of the Claude Bernard Lyon 1 University on February 10, 2023.

Earth Sciences - 09.02.2023
Mission to monitor seafloor fault at foot of Mount Etna
Mission to monitor seafloor fault at foot of Mount Etna
The North Alfeo Fault runs across the seafloor at the base of Mount Etna, the tallest and currently most active European volcano, next to an urban area with a population of one million. The Focus project seeks to better understand seismic processes in action and allow for surveillance of movement along the fault.

Life Sciences - 08.02.2023
Mandrills teach their daughters good hygiene practices
Humans are not the only ones to teach their children good hygiene practices - mandrills do it too. In these primates, where many individuals are infected with contagious gastrointestinal parasites, some females systematically avoid grooming the peri-anal region of their groupmates.

Life Sciences - Agronomy / Food Science - 08.02.2023
Discovery of a protein’s key role in plant metabolism
Publication of the RDP in the journal The Plant Cell on February 8, 2023. Press realease of the INRAE on February 8, 2023. Nitrogen is an essential element for plant growth and therefore agricultural production. Understanding how plants assimilate nitrogen is essential for developing sustainable agriculture using less fertiliser.

Environment - 06.02.2023
Discovery of an alternative organic synthesis route in hydrothermal environments
Publication of the LGL-TPE in the journal Nature Communications on January 21, 2023. Communication of the CNRS-INSU on February 3, 2023. The abiotic reactions that allow the formation of complex, potentially prebiotic organic molecules are a missing key to determining where life may have emerged. The limited variety and simplicity of the abiotic organic molecules observed have long discredited the theory of a hydrothermal origin for the emergence of life on Earth.
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