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Life Sciences
Results 1 - 20 of 315.
Alzheimer’s disease: new contrast agents
Publication of the Chemistry Laboratory in the journal Nanomedicine on March 17, 2023. Communication of the CNRS-INC on March 20, 2023. A consortium of European researchers led by two Lyon laboratories - the Chemistry Laboratory (CNRS/ENS de Lyon/Université Claude Bernard Lyon 1) and the Lyon Neuroscience Research Center ( CNRS/Claude Bernard Lyon 1 university/Jean Monnet University/Inserm) - is proposing a new "multi-technique" imaging agent (MRI, X-ray, fluorescence..) targeting amyloid-? (A?) plaques, the first pathological signs of Alzheimer's disease (AD).
Publication of the Chemistry Laboratory in the journal Nanomedicine on March 17, 2023. Communication of the CNRS-INC on March 20, 2023. A consortium of European researchers led by two Lyon laboratories - the Chemistry Laboratory (CNRS/ENS de Lyon/Université Claude Bernard Lyon 1) and the Lyon Neuroscience Research Center ( CNRS/Claude Bernard Lyon 1 university/Jean Monnet University/Inserm) - is proposing a new "multi-technique" imaging agent (MRI, X-ray, fluorescence..) targeting amyloid-? (A?) plaques, the first pathological signs of Alzheimer's disease (AD).
Laure Bonnaud-Ponticelli: ’The octopus has phenomenal analytical capacities!’
Gone are the days when the octopus was, in the collective imagination, a frightening sea monster attacking Jules Verne's Nautilus. The image of the octopus has now changed. For example, the cephalopod took on the pseudonym Paul during the 2010 soccer World Cup, and made predictions about the outcomes of games (more or less successfully.
Gone are the days when the octopus was, in the collective imagination, a frightening sea monster attacking Jules Verne's Nautilus. The image of the octopus has now changed. For example, the cephalopod took on the pseudonym Paul during the 2010 soccer World Cup, and made predictions about the outcomes of games (more or less successfully.
Can artificial intelligence match how the brain processes sound ?
Without realising it, our brain continuously processes sounds and infers semantic information, such as the presence of birds in a tree based on hearing their song.
Without realising it, our brain continuously processes sounds and infers semantic information, such as the presence of birds in a tree based on hearing their song.
Pre- and Postnatal Chlordecone Exposure Could Affect the Cognitive Development and Behavior of Children
Chlordecone is an organochlorine insecticide that was used in the French West Indies from 1973 to 1993 to control the banana root borer. Adobe Stock Despite the fact that chlordecone has not been used as an insecticide in the French West Indies for 30 years now, its persistence in the environment continues to contaminate the populations.
Chlordecone is an organochlorine insecticide that was used in the French West Indies from 1973 to 1993 to control the banana root borer. Adobe Stock Despite the fact that chlordecone has not been used as an insecticide in the French West Indies for 30 years now, its persistence in the environment continues to contaminate the populations.
How the microbiota stimulates growth
1 While insulin-like growth factor 1 (IGF-1), mainly produced by the liver, has a chemical structure similar to that of insulin, these hormones have distinct functions: IGF-1 stimulates tissue and skeletal growth, whereas insulin regulates energy metabolism as required for growth. The gut microbiota is now thought to constitute an organ in its own right.
1 While insulin-like growth factor 1 (IGF-1), mainly produced by the liver, has a chemical structure similar to that of insulin, these hormones have distinct functions: IGF-1 stimulates tissue and skeletal growth, whereas insulin regulates energy metabolism as required for growth. The gut microbiota is now thought to constitute an organ in its own right.
A blood factor involved in depression
A small group of neural stem cells isolated from mice and cultured in vitro observed under a confocal microscope. The process of aging is often related to the onset of cognitive decline, depression and memory loss. Scientists from the Institut Pasteur, CNRS and Inserm have discovered that administration of the GDF11 protein, which is known to regenerate murine neural stem cells, improves cognitive abilities and reduces the depressive state in aged mice.
A small group of neural stem cells isolated from mice and cultured in vitro observed under a confocal microscope. The process of aging is often related to the onset of cognitive decline, depression and memory loss. Scientists from the Institut Pasteur, CNRS and Inserm have discovered that administration of the GDF11 protein, which is known to regenerate murine neural stem cells, improves cognitive abilities and reduces the depressive state in aged mice.
Who are the first ancestors of present-day fish?
What is the origin of the ancestors of present-day fish? What species evolved from them? A 50-year-old scientific controversy revolved around the question of which group, the "bony-tongues” or the "eels”, was the oldest. A study by INRAE, the CNRS, the Pasteur Institute, Inserm and the Muséum National d'Histoire Naturelle , has just put an end to the debate by showing through genomic analysis that these fishes are in fact one and the same group, given the rather peculiar name of "Eloposteoglossocephala”.
What is the origin of the ancestors of present-day fish? What species evolved from them? A 50-year-old scientific controversy revolved around the question of which group, the "bony-tongues” or the "eels”, was the oldest. A study by INRAE, the CNRS, the Pasteur Institute, Inserm and the Muséum National d'Histoire Naturelle , has just put an end to the debate by showing through genomic analysis that these fishes are in fact one and the same group, given the rather peculiar name of "Eloposteoglossocephala”.
Mandrills teach their daughters good hygiene practices
Humans are not the only ones to teach their children good hygiene practices - mandrills do it too. In these primates, where many individuals are infected with contagious gastrointestinal parasites, some females systematically avoid grooming the peri-anal region of their groupmates.
Humans are not the only ones to teach their children good hygiene practices - mandrills do it too. In these primates, where many individuals are infected with contagious gastrointestinal parasites, some females systematically avoid grooming the peri-anal region of their groupmates.
Discovery of a protein’s key role in plant metabolism
Publication of the RDP in the journal The Plant Cell on February 8, 2023. Press realease of the INRAE on February 8, 2023. Nitrogen is an essential element for plant growth and therefore agricultural production. Understanding how plants assimilate nitrogen is essential for developing sustainable agriculture using less fertiliser.
Publication of the RDP in the journal The Plant Cell on February 8, 2023. Press realease of the INRAE on February 8, 2023. Nitrogen is an essential element for plant growth and therefore agricultural production. Understanding how plants assimilate nitrogen is essential for developing sustainable agriculture using less fertiliser.
Two proteins join forces to make flowers
What mechanisms are behind the formation of flowers? To answer this question a 25-year-old enigma has just been solved: the role of UFO protein in the flower's formation process. While its nature suggested that it destroys its partners, this protein is in fact an aid to the birth of a flower when coupled to the LEAFY protein.
What mechanisms are behind the formation of flowers? To answer this question a 25-year-old enigma has just been solved: the role of UFO protein in the flower's formation process. While its nature suggested that it destroys its partners, this protein is in fact an aid to the birth of a flower when coupled to the LEAFY protein.
Cystic Fibrosis: A New Therapeutic Avenue Thanks to Research Into an Edible Mushroom
Lepista flaccida , an edible mushroom found in the northern hemisphere, was the focus of research by French teams into ways of correcting certain genetic mutations known as nonsense mutations. MNHN/CNRS - Christine Bailly A molecule obtained from an edible mushroom could open up therapeutic avenues for patients with cystic fibrosis, the most frequent rare genetic disease.
Lepista flaccida , an edible mushroom found in the northern hemisphere, was the focus of research by French teams into ways of correcting certain genetic mutations known as nonsense mutations. MNHN/CNRS - Christine Bailly A molecule obtained from an edible mushroom could open up therapeutic avenues for patients with cystic fibrosis, the most frequent rare genetic disease.
Discovery of a circovirus involved in human hepatitis
Scientists from the Institut Pasteur, Necker-Enfants Malades Hospital (AP-HP), Inserm in the Imagine Institute, Université Paris Cité and the Alfort National Veterinary School (EnvA) have identified a previously unknown species of circovirus, provisionally named human circovirus 1 (HCirV-1). Circoviruses are a family of small, highly resistant DNA viruses that were initially identified in 1974 in various animal species, where they can cause respiratory, renal, dermatological and reproductive problems.
Scientists from the Institut Pasteur, Necker-Enfants Malades Hospital (AP-HP), Inserm in the Imagine Institute, Université Paris Cité and the Alfort National Veterinary School (EnvA) have identified a previously unknown species of circovirus, provisionally named human circovirus 1 (HCirV-1). Circoviruses are a family of small, highly resistant DNA viruses that were initially identified in 1974 in various animal species, where they can cause respiratory, renal, dermatological and reproductive problems.
Dengue and Zika Viruses: Towards a Better Understanding of the Mechanisms of Transmission
The Aedes aegypti mosquito is the main vector of dengue, Zika virus infection, chikungunya, and yellow fever. © Adobe Stock Aedes mosquitoes are the principal vectors of dengue and other arboviruses, including Zika, for which no vaccines or antiviral treatments currently exist. Understanding the factors that influence the transmission of arboviruses from mosquitoes to humans is therefore a priority because it could guide the implementation of public health measures that could limit or even prevent epidemics.
The Aedes aegypti mosquito is the main vector of dengue, Zika virus infection, chikungunya, and yellow fever. © Adobe Stock Aedes mosquitoes are the principal vectors of dengue and other arboviruses, including Zika, for which no vaccines or antiviral treatments currently exist. Understanding the factors that influence the transmission of arboviruses from mosquitoes to humans is therefore a priority because it could guide the implementation of public health measures that could limit or even prevent epidemics.
Covid-19: genetic defects responsible for multisystemic inflammatory syndrome in children
The team from the Human Genetics of Infectious Diseases Laboratory of the Necker-Enfants malades AP-HP Hospital, Inserm, Université Paris Cité within the Imagine Institute, leading the international consortium COVID Human Genetic Effort ( www.covidhge.com ) coordinated by Prof. Jean-Laurent Casanova and Prof. Laurent Abel, has discovered genetic defects responsible for multi-systemic inflammatory syndrome in children (MIS-C), following infection with SARS-CoV-2.
The team from the Human Genetics of Infectious Diseases Laboratory of the Necker-Enfants malades AP-HP Hospital, Inserm, Université Paris Cité within the Imagine Institute, leading the international consortium COVID Human Genetic Effort ( www.covidhge.com ) coordinated by Prof. Jean-Laurent Casanova and Prof. Laurent Abel, has discovered genetic defects responsible for multi-systemic inflammatory syndrome in children (MIS-C), following infection with SARS-CoV-2.
Microfibers of the Mediterranean
A consortium of bacteria form on the microfibers of the Mediterranean Sea, becoming "floating homes for bacteria". Maria Luiza Pedrotti, a CNRS researcher at the Villefranche-sur-Mer oceanography laboratory has reported the presence of a pathogenic bacterium on the tiny textile fibers found in the deep blue sea.
A consortium of bacteria form on the microfibers of the Mediterranean Sea, becoming "floating homes for bacteria". Maria Luiza Pedrotti, a CNRS researcher at the Villefranche-sur-Mer oceanography laboratory has reported the presence of a pathogenic bacterium on the tiny textile fibers found in the deep blue sea.
Microfibers of the Mediterranean
A consortium of bacteria form on the microfibers of the Mediterranean Sea, becoming "floating homes for bacteria". Maria Luiza Pedrotti, a CNRS researcher at the Villefranche-sur-Mer oceanography laboratory has reported the presence of a pathogenic bacterium on the tiny textile fibers found in the deep blue sea.
A consortium of bacteria form on the microfibers of the Mediterranean Sea, becoming "floating homes for bacteria". Maria Luiza Pedrotti, a CNRS researcher at the Villefranche-sur-Mer oceanography laboratory has reported the presence of a pathogenic bacterium on the tiny textile fibers found in the deep blue sea.
Microfibers of the Mediterranean
A consortium of bacteria form on the microfibers of the Mediterranean Sea, becoming "floating homes for bacteria". Maria Luiza Pedrotti, a CNRS researcher at the Villefranche-sur-Mer oceanography laboratory has reported the presence of a pathogenic bacterium on the tiny textile fibers found in the deep blue sea.
A consortium of bacteria form on the microfibers of the Mediterranean Sea, becoming "floating homes for bacteria". Maria Luiza Pedrotti, a CNRS researcher at the Villefranche-sur-Mer oceanography laboratory has reported the presence of a pathogenic bacterium on the tiny textile fibers found in the deep blue sea.
COVID-19: a respiratory vaccine effective in mice
Less known to the general public, mucosal vaccination via the mucus membranes could provide robust protection against SARS-CoV-2 infections. Immune cells in the nose and lungs are considered better prepared to encounter and block the virus that causes COVID-19. An international research team has just demonstrated that its mucosal DNA vaccine is capable of ensuring the total survival of a group of mice infected with a version of the virus adapted to this species, whereas the latter kills 100% of unvaccinated mice 1 .
Less known to the general public, mucosal vaccination via the mucus membranes could provide robust protection against SARS-CoV-2 infections. Immune cells in the nose and lungs are considered better prepared to encounter and block the virus that causes COVID-19. An international research team has just demonstrated that its mucosal DNA vaccine is capable of ensuring the total survival of a group of mice infected with a version of the virus adapted to this species, whereas the latter kills 100% of unvaccinated mice 1 .
CEA-Leti Presents RRAM’s -Promising Advantages- For Neuromorphic/In-Memory Computing at IEDM 2022
A CEA-Leti tutorial presented at IEDM 2022 highlighted promising advantages that resistive random-access memory (RRAM) technologies hold for implementing novel neuromorphic/in-memory computing systems for massively parallel, low-power and low-latency computation. In a presentation titled "Resistive Memories-Based Concepts for Neuromorphic Computing" , Elisa Vianello, CEA-Leti's edge AI program manager, said RRAMs, aka memristors, offer advantages in energy efficiency and computing power when processing AI workloads.
A CEA-Leti tutorial presented at IEDM 2022 highlighted promising advantages that resistive random-access memory (RRAM) technologies hold for implementing novel neuromorphic/in-memory computing systems for massively parallel, low-power and low-latency computation. In a presentation titled "Resistive Memories-Based Concepts for Neuromorphic Computing" , Elisa Vianello, CEA-Leti's edge AI program manager, said RRAMs, aka memristors, offer advantages in energy efficiency and computing power when processing AI workloads.
ASD: Towards a Better Understanding of the Molecular Mechanisms of Autism
While great progress has been made in recent years in the understanding of autism spectrum disorder (ASD), its underlying molecular mechanisms remain fairly poorly documented.
While great progress has been made in recent years in the understanding of autism spectrum disorder (ASD), its underlying molecular mechanisms remain fairly poorly documented.