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Health - Life Sciences - 17.05.2023
Women and Parkinson’s Disease: Physical Activity Found to Be Beneficial More Than Twenty Years Before Diagnosis
Although physical activity is regularly discussed as being one of the avenues for preventing Parkinson's disease (PD), studies so far had been unable to eliminate certain biases or had not focused on its specific role in women. Researchers from Inserm, Université Paris-Saclay and Université de Versailles Saint-Quentin-en-Yvelines (UVSQ) with the Gustave Roussy Institute studied the impact of physical activity on the development of PD in nearly 100,000 women from the French cohort E3N followed up over 29 years.

Health - Life Sciences - 16.05.2023
Eating Broccoli to Limit Skin Allergies
Eating Broccoli to Limit Skin Allergies
The severity of skin allergies can vary depending on many environmental factors, including diet. However, the role of specific nutrients had not been well documented until now. In a new study, researchers from Inserm and Institut Curie at the Immunity and Cancer unit have shown that the absence in the diet of compounds found in certain vegetables, particularly broccoli and cabbage, could worsen skin allergies in animal models.

Life Sciences - Health - 10.05.2023
Seeing with Sound
Restoring sight to blind people thanks to a therapy that combines genetics and ultrasound is the hope of Serge Picaud's team, director of the Vision Institute *, and the Physics for Medicine Laboratory of the ESPCI ** in partnership with the Institute of Molecular and Clinical Ophthalmology of Basel.

Health - Life Sciences - 03.05.2023
Long COVID: The Persistence of SARS-CoV-2 in the Mucous Membranes May Be A Factor
This transmission electron microscope image shows SARS-CoV-2, isolated from a patient in the U.S., emerging from the surface of cells cultivated in a laboratory. National Institute of Allergy and Infectious Diseases-Rocky Mountain Laboratories, NIH. Public domain. Several months after infection with SARS-CoV-2, some patients still have symptoms: a phenomenon commonly referred to as "long COVID”.

Life Sciences - Environment - 19.04.2023
New viruses related to both giant viruses and herpesviruses
New viruses related to both giant viruses and herpesviruses
A team from the CEA and CNRS have discovered the existence of mirusviruses: a major group of viruses abundant on the surface of the seas and oceans, where they infect single-celled plankton. These findings appear in Nature on 19 April. The discovery provides a better understanding of the scope of ocean biodiversity and the importance of viruses in these ecosystems.

Health - Life Sciences - 18.04.2023
A sponsorship from Quercia Venture Management in support of obesity research
An innovative research program on the theme of "Nutrition and Obesity: Systemic Approaches", led by Professor Karine Clément and her team, benefits from the sponsorship of Quercia Venture Management. We are currently experiencing a global epidemic of obesity resulting from the interactions between our genetic heritage and numerous environmental factors.

Life Sciences - 09.04.2023
Species that eliminate a third of their genome in somatic cells
Publication of the LBMC in the journal Current Biology, on August 21, 2023. Communication of CNRS-INSB on August 30, 2023. Some animal species systematically destroy part of their DNA in their somatic cells. Why do they do this? But how? This programmed elimination of the genome, discovered 150 years ago, remains mysterious in the absence of suitable means of study.

Life Sciences - Health - 03.04.2023
Restoring Vision Through a New Brain-Machine Interface: Sonogenetic Therapy
Sonogenetic therapy consists of genetically modifying certain neurons in order to activate them remotely by ultrasound. © Alexandre Dizeux/Physics for Medicine Paris Restore vision using a combination of ultrasound and genetics? This is the goal of an international team led by Inserm research directors Mickael Tanter and Serge Picaud from Paris' Physics for Medicine unit (ESPCI Paris/PSL Université/Inserm/CNRS) and Vision Institute (Sorbonne Université/Inserm/CNRS), respectively, in partnership with the Institute of Molecular and Clinical Ophthalmology in Basel.

Health - Life Sciences - 27.03.2023
Towards a Better Understanding of the Role of Male Hormones in Women with Multiple Sclerosis
The image shows the brain region where demyelination is typically induced. The red cells correspond to all of the microglial cells with inflammatory properties when demyelination has just occurred. If the spontaneous regeneration process of myelin is effective, their inflammatory nature then diminishes in favor of an anti-inflammatory and pro-regenerative nature.

Health - Life Sciences - 23.03.2023
Alzheimer’s disease: new contrast agents
Publication of the Chemistry Laboratory in the journal Nanomedicine on March 17, 2023. Communication of the CNRS-INC on March 20, 2023. A consortium of European researchers led by two Lyon laboratories - the Chemistry Laboratory (CNRS/ENS de Lyon/Université Claude Bernard Lyon 1) and the Lyon Neuroscience Research Center ( CNRS/Claude Bernard Lyon 1 university/Jean Monnet University/Inserm) - is proposing a new "multi-technique" imaging agent (MRI, X-ray, fluorescence..) targeting amyloid-? (A?) plaques, the first pathological signs of Alzheimer's disease (AD).

Life Sciences - Environment - 16.03.2023
Laure Bonnaud-Ponticelli: 'The octopus has phenomenal analytical capacities!'
Laure Bonnaud-Ponticelli: ’The octopus has phenomenal analytical capacities!’
Gone are the days when the octopus was, in the collective imagination, a frightening sea monster attacking Jules Verne's Nautilus. The image of the octopus has now changed. For example, the cephalopod took on the pseudonym Paul during the 2010 soccer World Cup, and made predictions about the outcomes of games (more or less successfully.

Life Sciences - Computer Science - 16.03.2023
Can artificial intelligence match how the brain processes sound ?
Without realising it, our brain continuously processes sounds and infers semantic information, such as the presence of birds in a tree based on hearing their song.

Life Sciences - Health - 27.02.2023
Pre- and Postnatal Chlordecone Exposure Could Affect the Cognitive Development and Behavior of Children
Chlordecone is an organochlorine insecticide that was used in the French West Indies from 1973 to 1993 to control the banana root borer. Adobe Stock Despite the fact that chlordecone has not been used as an insecticide in the French West Indies for 30 years now, its persistence in the environment continues to contaminate the populations.

Life Sciences - Health - 23.02.2023
How the microbiota stimulates growth
How the microbiota stimulates growth
1 While insulin-like growth factor 1 (IGF-1), mainly produced by the liver, has a chemical structure similar to that of insulin, these hormones have distinct functions: IGF-1 stimulates tissue and skeletal growth, whereas insulin regulates energy metabolism as required for growth. The gut microbiota is now thought to constitute an organ in its own right.

Life Sciences - Psychology - 21.02.2023
A blood factor involved in depression
A small group of neural stem cells isolated from mice and cultured in vitro observed under a confocal microscope. The process of aging is often related to the onset of cognitive decline, depression and memory loss. Scientists from the Institut Pasteur, CNRS and Inserm have discovered that administration of the GDF11 protein, which is known to regenerate murine neural stem cells, improves cognitive abilities and reduces the depressive state in aged mice.

Life Sciences - 13.02.2023
Who are the first ancestors of present-day fish?
Who are the first ancestors of present-day fish?
What is the origin of the ancestors of present-day fish? What species evolved from them? A 50-year-old scientific controversy revolved around the question of which group, the "bony-tongues” or the "eels”, was the oldest. A study by INRAE, the CNRS, the Pasteur Institute, Inserm and the Muséum National d'Histoire Naturelle , has just put an end to the debate by showing through genomic analysis that these fishes are in fact one and the same group, given the rather peculiar name of "Eloposteoglossocephala”.

Life Sciences - 08.02.2023
Mandrills teach their daughters good hygiene practices
Humans are not the only ones to teach their children good hygiene practices - mandrills do it too. In these primates, where many individuals are infected with contagious gastrointestinal parasites, some females systematically avoid grooming the peri-anal region of their groupmates.

Life Sciences - Agronomy / Food Science - 08.02.2023
Discovery of a protein’s key role in plant metabolism
Publication of the RDP in the journal The Plant Cell on February 8, 2023. Press realease of the INRAE on February 8, 2023. Nitrogen is an essential element for plant growth and therefore agricultural production. Understanding how plants assimilate nitrogen is essential for developing sustainable agriculture using less fertiliser.

Life Sciences - 03.02.2023
Two proteins join forces to make flowers
What mechanisms are behind the formation of flowers? To answer this question a 25-year-old enigma has just been solved: the role of UFO protein in the flower's formation process. While its nature suggested that it destroys its partners, this protein is in fact an aid to the birth of a flower when coupled to the LEAFY protein.

Health - Life Sciences - 26.01.2023
Cystic Fibrosis: A New Therapeutic Avenue Thanks to Research Into an Edible Mushroom
Cystic Fibrosis: A New Therapeutic Avenue Thanks to Research Into an Edible Mushroom
Lepista flaccida , an edible mushroom found in the northern hemisphere, was the focus of research by French teams into ways of correcting certain genetic mutations known as nonsense mutations. MNHN/CNRS - Christine Bailly A molecule obtained from an edible mushroom could open up therapeutic avenues for patients with cystic fibrosis, the most frequent rare genetic disease.