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Pharmacology - 25.11.2019
Pharmacology - Life Sciences - 21.11.2019
Life Sciences - Pharmacology - 18.07.2019 
New prebiotics: benefits without the downsides?
Prebiotics are currently a preferred treatment for certain metabolic disorders, as they can restore the balance of dysfunctional gut microbiota, and improve the body's metabolism. However, these substances have to be used at high doses, which can result in patients experiencing bloating and flatulence.
Innovation - Pharmacology - 22.05.2019 
MaaT Pharma expands patent portfolio with three granted patents covering its microbiome restoration biotherapeutic platform
First patents to cover the fundamental processes for accessing the human gut microbiome as biotherapeutics. MaaT Pharma's microbiome sample collection and administration devices receive CE mark for use in collecting and administrating gut-derived samples as biotherapeutics to patients.
Pharmacology - Innovation - 27.02.2019 
CEA-Leti Breakthrough Opens Path To New Vaccine for HIV using Lipid-Nanoparticle-Delivery Technology
Lipidots Platform Strengthens Immune Response to Protein That Is Key to HIV Vaccine; Results Presented in Nature Publishing Group's npj Vaccines GRENOBLE, France - Feb. 27, 2019 - Leti, a research institute of CEA Tech, in collaboration with CEA's Fundamental Research Division , has developed a new vaccine approach for HIV based on engineered lipid nanoparticles that deliver p24 - a viral protein that is key to an HIV vaccine- and optimize the CpG adjuvant's effect.
Life Sciences - Pharmacology - 21.12.2018 
A novel antibiotic resistance mechanism
Bacteria make use of a number of natural resistance strategies to overcome antibiotics. And it seems that this bacterial toolbox may be much more varied than previously thought. Scientists at the Institut Pasteur, in collaboration with Inserm, INRA, the CNRS and the Weizmann Institute of Science in Israel, have recently revealed an entirely unknown resistance mechanism in Listeria monocytogenes bacteria.
Pharmacology
Results 1 - 6 of 6.
Missing self triggers NK cell-mediated chronic vascular rejection of solid organ transplants
Publication by CIRI on November 25, 2019. Dogma in transplantation holds that microvascular inflammation (MVI) triggered by recipient's antibody response against alloantigens (antibody-mediated rejection) is the main cause of graft failure. Analysis of a cohort of 129 renal recipients with MVI on graft biopsy shows that, in half of the cases, histological lesions are not mediated by antibodies.
Publication by CIRI on November 25, 2019. Dogma in transplantation holds that microvascular inflammation (MVI) triggered by recipient's antibody response against alloantigens (antibody-mediated rejection) is the main cause of graft failure. Analysis of a cohort of 129 renal recipients with MVI on graft biopsy shows that, in half of the cases, histological lesions are not mediated by antibodies.
Get randomly lost, get home sooner
In a multicellular organism, gene expression regulation allows cells to live, divide and ensure their proper physiological role. The molecular nature of this process (e.g. low molecule number, Brownian movements...) involves random variations. Indeed, with the same genetic background, two neighbor cells do not express their genes in the same way.
In a multicellular organism, gene expression regulation allows cells to live, divide and ensure their proper physiological role. The molecular nature of this process (e.g. low molecule number, Brownian movements...) involves random variations. Indeed, with the same genetic background, two neighbor cells do not express their genes in the same way.
Prebiotics are currently a preferred treatment for certain metabolic disorders, as they can restore the balance of dysfunctional gut microbiota, and improve the body's metabolism. However, these substances have to be used at high doses, which can result in patients experiencing bloating and flatulence.
First patents to cover the fundamental processes for accessing the human gut microbiome as biotherapeutics. MaaT Pharma's microbiome sample collection and administration devices receive CE mark for use in collecting and administrating gut-derived samples as biotherapeutics to patients.
Lipidots Platform Strengthens Immune Response to Protein That Is Key to HIV Vaccine; Results Presented in Nature Publishing Group's npj Vaccines GRENOBLE, France - Feb. 27, 2019 - Leti, a research institute of CEA Tech, in collaboration with CEA's Fundamental Research Division , has developed a new vaccine approach for HIV based on engineered lipid nanoparticles that deliver p24 - a viral protein that is key to an HIV vaccine- and optimize the CpG adjuvant's effect.
Bacteria make use of a number of natural resistance strategies to overcome antibiotics. And it seems that this bacterial toolbox may be much more varied than previously thought. Scientists at the Institut Pasteur, in collaboration with Inserm, INRA, the CNRS and the Weizmann Institute of Science in Israel, have recently revealed an entirely unknown resistance mechanism in Listeria monocytogenes bacteria.
