News in Brief
Social Sciences - Jun 18
What Do We See When We Look at Networks. An Introduction to Visual Network Analysis and Force-Directed Layouts
What Do We See When We Look at Networks. An Introduction to Visual Network Analysis and Force-Directed Layouts
Environment - Jun 17
Impact glasses from Belize represent tektites from the Pleistocene Pantasma impact crater in Nicaragua
Impact glasses from Belize represent tektites from the Pleistocene Pantasma impact crater in Nicaragua
Physics - Jun 15
CEA-Leti collaborates with siemens to launch process design kit that supports multiple technologies, simplifies creation of optical circuits
CEA-Leti collaborates with siemens to launch process design kit that supports multiple technologies, simplifies creation of optical circuits
Environment - Jun 8
Ocean and climate: French research called on to take part in a Priority Research Programme
Ocean and climate: French research called on to take part in a Priority Research Programme
Economics - May 31
CEA-Leti Launches Direct Analysis to Bring Speed And Efficiency to Food-Safety Testing
CEA-Leti Launches Direct Analysis to Bring Speed And Efficiency to Food-Safety Testing
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Health - Pharmacology - 01.12.2020 
Deciphering the energetic code of cells for better anticancer therapies
A procedure that may help personalise anticancer therapies has just been developed by the CNRS, INSERM, and Aix-Marseille University scientists at the Centre d'Immunologie de Marseille-Luminy, in association with colleagues from the University of California San Francisco and the Marseille Public University Hospital System (AP-HM), with support from Canceropôle Provence-Alpes-Côte d'Azur.
Health - Pharmacology - 04.05.2020
Pharmacology - 25.11.2019
Pharmacology - Life Sciences - 21.11.2019
Life Sciences - Pharmacology - 18.07.2019 
New prebiotics: benefits without the downsides?
Prebiotics are currently a preferred treatment for certain metabolic disorders, as they can restore the balance of dysfunctional gut microbiota, and improve the body's metabolism. However, these substances have to be used at high doses, which can result in patients experiencing bloating and flatulence.
Innovation - Pharmacology - 22.05.2019 
MaaT Pharma expands patent portfolio with three granted patents covering its microbiome restoration biotherapeutic platform
First patents to cover the fundamental processes for accessing the human gut microbiome as biotherapeutics. MaaT Pharma's microbiome sample collection and administration devices receive CE mark for use in collecting and administrating gut-derived samples as biotherapeutics to patients.
Pharmacology - Innovation - 27.02.2019 
CEA-Leti Breakthrough Opens Path To New Vaccine for HIV using Lipid-Nanoparticle-Delivery Technology
Lipidots Platform Strengthens Immune Response to Protein That Is Key to HIV Vaccine; Results Presented in Nature Publishing Group's npj Vaccines GRENOBLE, France - Feb. 27, 2019 - Leti, a research institute of CEA Tech, in collaboration with CEA's Fundamental Research Division , has developed a new vaccine approach for HIV based on engineered lipid nanoparticles that deliver p24 - a viral protein that is key to an HIV vaccine- and optimize the CpG adjuvant's effect.
Life Sciences - Pharmacology - 21.12.2018 
A novel antibiotic resistance mechanism
Bacteria make use of a number of natural resistance strategies to overcome antibiotics. And it seems that this bacterial toolbox may be much more varied than previously thought. Scientists at the Institut Pasteur, in collaboration with Inserm, INRA, the CNRS and the Weizmann Institute of Science in Israel, have recently revealed an entirely unknown resistance mechanism in Listeria monocytogenes bacteria.
Pharmacology
Results 1 - 8 of 8.
A procedure that may help personalise anticancer therapies has just been developed by the CNRS, INSERM, and Aix-Marseille University scientists at the Centre d'Immunologie de Marseille-Luminy, in association with colleagues from the University of California San Francisco and the Marseille Public University Hospital System (AP-HM), with support from Canceropôle Provence-Alpes-Côte d'Azur.
Six new research projects concerning Covid-19
On April 10, 2020, ANR announced the funding of 86 projects concerning Covid-19. Six are associated with ENS de Lyon laboratories. The SARS-CoV-2 infection is a global emergency for human health. The interferon response is the body's first barrier to defending viral infections. This host response is initiated by the recognition of viral elements by receptor and leads to the production of molecules, including interferon, that alert surrounding cells.
On April 10, 2020, ANR announced the funding of 86 projects concerning Covid-19. Six are associated with ENS de Lyon laboratories. The SARS-CoV-2 infection is a global emergency for human health. The interferon response is the body's first barrier to defending viral infections. This host response is initiated by the recognition of viral elements by receptor and leads to the production of molecules, including interferon, that alert surrounding cells.
Missing self triggers NK cell-mediated chronic vascular rejection of solid organ transplants
Publication by CIRI on November 25, 2019. Dogma in transplantation holds that microvascular inflammation (MVI) triggered by recipient's antibody response against alloantigens (antibody-mediated rejection) is the main cause of graft failure. Analysis of a cohort of 129 renal recipients with MVI on graft biopsy shows that, in half of the cases, histological lesions are not mediated by antibodies.
Publication by CIRI on November 25, 2019. Dogma in transplantation holds that microvascular inflammation (MVI) triggered by recipient's antibody response against alloantigens (antibody-mediated rejection) is the main cause of graft failure. Analysis of a cohort of 129 renal recipients with MVI on graft biopsy shows that, in half of the cases, histological lesions are not mediated by antibodies.
Get randomly lost, get home sooner
In a multicellular organism, gene expression regulation allows cells to live, divide and ensure their proper physiological role. The molecular nature of this process (e.g. low molecule number, Brownian movements...) involves random variations. Indeed, with the same genetic background, two neighbor cells do not express their genes in the same way.
In a multicellular organism, gene expression regulation allows cells to live, divide and ensure their proper physiological role. The molecular nature of this process (e.g. low molecule number, Brownian movements...) involves random variations. Indeed, with the same genetic background, two neighbor cells do not express their genes in the same way.
Prebiotics are currently a preferred treatment for certain metabolic disorders, as they can restore the balance of dysfunctional gut microbiota, and improve the body's metabolism. However, these substances have to be used at high doses, which can result in patients experiencing bloating and flatulence.
First patents to cover the fundamental processes for accessing the human gut microbiome as biotherapeutics. MaaT Pharma's microbiome sample collection and administration devices receive CE mark for use in collecting and administrating gut-derived samples as biotherapeutics to patients.
Lipidots Platform Strengthens Immune Response to Protein That Is Key to HIV Vaccine; Results Presented in Nature Publishing Group's npj Vaccines GRENOBLE, France - Feb. 27, 2019 - Leti, a research institute of CEA Tech, in collaboration with CEA's Fundamental Research Division , has developed a new vaccine approach for HIV based on engineered lipid nanoparticles that deliver p24 - a viral protein that is key to an HIV vaccine- and optimize the CpG adjuvant's effect.
Bacteria make use of a number of natural resistance strategies to overcome antibiotics. And it seems that this bacterial toolbox may be much more varied than previously thought. Scientists at the Institut Pasteur, in collaboration with Inserm, INRA, the CNRS and the Weizmann Institute of Science in Israel, have recently revealed an entirely unknown resistance mechanism in Listeria monocytogenes bacteria.
News in Brief
Social Sciences - Jun 18
What Do We See When We Look at Networks. An Introduction to Visual Network Analysis and Force-Directed Layouts
What Do We See When We Look at Networks. An Introduction to Visual Network Analysis and Force-Directed Layouts
Environment - Jun 17
Impact glasses from Belize represent tektites from the Pleistocene Pantasma impact crater in Nicaragua
Impact glasses from Belize represent tektites from the Pleistocene Pantasma impact crater in Nicaragua
Physics - Jun 15
CEA-Leti collaborates with siemens to launch process design kit that supports multiple technologies, simplifies creation of optical circuits
CEA-Leti collaborates with siemens to launch process design kit that supports multiple technologies, simplifies creation of optical circuits
Environment - Jun 8
Ocean and climate: French research called on to take part in a Priority Research Programme
Ocean and climate: French research called on to take part in a Priority Research Programme
Economics - May 31
CEA-Leti Launches Direct Analysis to Bring Speed And Efficiency to Food-Safety Testing
CEA-Leti Launches Direct Analysis to Bring Speed And Efficiency to Food-Safety Testing