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Health - Life Sciences - 21.09.2021
Breast cancers: ruptures in cell nuclei promotes tumor invasion
Breast cancers: ruptures in cell nuclei promotes tumor invasion
Cell nuclei protect the DNA. Nuclei can rupture when cells are deformed, causing DNA damage. In the case of breast cancer, this damage makes tumour cells more invasive, with increased risk of metastasis. When cells multiply and migrate, they can be compressed and their nucleus may break open. This phenomenon causes DNA damage.

Health - 26.08.2021
COVID-19: Will telecommuting strategies stop the virus from circulating?
How can we best organise on-site workplace and school attendance periods and remote work to slow the circulation of Sars-CoV-2? Is it better to separate classes? Bring your whole team in at the same time? Set this up on daily or weekly schedules? The COVID-19 pandemic has forced most countries to impose contact limitations in workplaces, universities and schools.

Health - 28.07.2021
Neandertal and Denisovan blood groups deciphered
Neandertal and Denisovan blood groups deciphered
The blood groups of three Neandertal females and one Denisovan female have been determined by a Marseille-based team including a palaeoanthropologist, population geneticists, and haematologists. Their research provides new data for understanding the origins, history, and health of these extinct hominin lineages.

Health - Life Sciences - 25.05.2021
Optogenetic Methods Restore Partial Vision in a Blind Patient
Optogenetic Methods Restore Partial Vision in a Blind Patient
Results of this research, a world-first, were published in  Nature Medicine on May 24th, 2021. An international research team has shown that optogenetic therapy has helped a patient with retinitis pigmentosa to partially regain visual function. This is a milestone step towards a type of gene therapy that could restore vision.

Health - Life Sciences - 13.04.2021
'All-in-One' Technique that Could Accelerate Phage-Therapy Diagnosis
’All-in-One’ Technique that Could Accelerate Phage-Therapy Diagnosis
Lensless Imaging System Affirms Phage Therapy's Value in Treating Serious Infection, Tracks Phage Resistance and Could Easily Be Implemented in Compact Devices at Phage Labs GRENOBLE, France - April 13, 2021 - A team of French and Swiss scientists has demonstrated a lensless imaging technique that could easily be implemented in cost-effective and compact devices in phage laboratories to accelerate phage-therapy diagnosis.

Life Sciences - Health - 06.04.2021
A protein with a dual role: both repair and mutation
A protein with a dual role: both repair and mutation
The Mfd protein repairs bacterial DNA, but can also, to scientists' surprise, promote mutation. Bacterial mutations can lead to antibiotic resistance. Understanding this second "role" of the Mfd protein opens up opportunities for combating antibiotic resistance, and also the resistance of tumours to anti-cancer drugs and therapies.

Health - Life Sciences - 18.03.2021
Targeting Cancer Detection & Identification of Microorganisms, CEA-Leti Develops Mid-Infrared, Spectral-Imaging Technique
Targeting Cancer Detection & Identification of Microorganisms, CEA-Leti Develops Mid-Infrared, Spectral-Imaging Technique
Presentations at Photonics West 2021 Show How Early-Stage Imaging System's Flexibility Can Be Applied Broadly in Medical Field GRENOBLE, France - March 18, 2021 - CEA-Leti scientists have developed a lensless, infrared spectral-imaging system for medical diagnostics. The first application is cancer detection in the tissue section and the second is the identification and discrimination of microorganisms, such as bacteria.

Health - Chemistry - 15.03.2021
Many Sunscreens Contain a Carcinogenic Compound
An organic sunscreen filter frequently used in sunscreens and anti-aging creams, octocrylene degrades within the bottles themselves into a known carcinogenic and endocrine disrupting compound: benzophenone.

Health - Mathematics - 04.03.2021
COVID-19 Screening: A New Model for Assessing the Efficiency of Group Testing
COVID-19 Screening: A New Model for Assessing the Efficiency of Group Testing
How best to evaluate the performance of a group testing strategy for the SARS-CoV-2 virus, which involves pooling samples from multiple individuals in order to conduct a single RT-PCR test on the whole group? To do precisely that, scientists from the CNRS, l'université Grenoble Alpes, and l'université Sorbonne Paris Nord 1 have developed a model that evaluates the efficiency of such tests.

Health - Environment - 11.02.2021
Heat islands and lack of running water promote dengue fever in Delhi, India
Heat islands and lack of running water promote dengue fever in Delhi, India
What if more inclusive urban planning for poor populations was key to fighting dengue fever? This is what researchers from the CNRS, the Institut Pasteur and the Indian Council of Medical Research 1 have demonstrated using a geographical approach applied to the greater city of Delhi (India). Their study is published in the journal PLOS Neglected Tropical Disease on 11 February 2021.

Health - Computer Science - 16.12.2020
An Interdisciplinary Approach for Technological Advancement
Sorbonne University Alliance Multidisciplinary research Mathematician Pascal Frey heads the Institute for Computational and Data Sciences (ISCD). Frey takes stock of ten years of interdisciplinary research and innovation around scientific computing, simulation and data analysis. The Institute is celebrating its tenth anniversary this year.

Health - Life Sciences - 16.12.2020
Alzheimer’s Disease: Regulating Copper in the Brain Stops Memory Loss Among Mice
Alzheimer's disease is characterized by the presence of amyloid plaques 1 in the patient's brain. These plaques sequester copper, and contain approximately five times as much as a healthy brain. Two CNRS scientists from the Coordination Chemistry Laboratory recently developed, with their colleagues from the Guangdong University of Technology and Shenzhen University (China), a molecule that regulates the circulation of copper in the brain.

Health - Pharmacology - 01.12.2020
Deciphering the energetic code of cells for better anticancer therapies
Deciphering the energetic code of cells for better anticancer therapies
A procedure that may help personalise anticancer therapies has just been developed by the CNRS, INSERM, and Aix-Marseille University scientists at the Centre d'Immunologie de Marseille-Luminy, in association with colleagues from the University of California San Francisco and the Marseille Public University Hospital System (AP-HM), with support from Canceropôle Provence-Alpes-Côte d'Azur.

Health - Life Sciences - 19.11.2020
Greater mosquito susceptibility to Zika virus fueled the epidemic
Greater mosquito susceptibility to Zika virus fueled the epidemic
The Zika virus has spread around the world over the last decade, causing millions of infections, some of which have been associated with congenital abnormalities and neurological disorders. Scientists from the CNRS, the Institut Pasteur, and the IRD 1 turned their attention to the main vector of the virus, the mosquito Aedes aegypti .

Health - Computer Science - 16.11.2020
How can we estimate the evolution of the reproductive number for Covid-19 in a better way?
A team of interdisciplinary researchers has demonstrated that convex optimization is an effective mathematical and numerical tool for a daily estimate of the evolution of the reproductive number for Covid-19, over time and across regions. Monitoring the spread of the Covid-19 pandemic is one of the major challenges of the global health crisis.

Health - Chemistry - 13.08.2020
The behaviour of therapeutic antibodies in immunotherapy
The behaviour of therapeutic antibodies in immunotherapy
Since the late 1990s, immunotherapy has been the frontline treatment against lymphomas where synthetic antibodies are used to stop the proliferation of cancerous white blood cells. However, in the more than 20 years since their use began, the molecular mechanisms that underlie this therapy are still little understood.

Health - Environment - 22.07.2020
Livestock expansion is a factor in global pandemics
Livestock expansion is a factor in global pandemics
The growth of global livestock farming is a threat to our biodiversity and also increases the health risks to both humans and domesticated animals. The patterns that link them are at the heart of a study published in Biological Conservation by a scientist from the Institute of Evolution Sciences of Montpellier (ISEM - CNRS/Université de Montpellier/IRD/EPHE) and the French Agricultural Research Centre for International Development's (CIRAD) ASTRE laboratory.

Health - Mathematics - 21.07.2020
"Winter is coming": the influence of seasonality on pathogen emergence
Seasonal fluctuations drive the dynamics of many infectious diseases. For instance, the flu spreads more readily in winter. Two scientists from the University of Nantes 1 and the CNRS 2 in Montpellier have developed a mathematical model to predict the risk of the emergence of an epidemic, depending on the time of the year at which the pathogen is introduced.

Health - 09.06.2020
Tuberculosis: discovery of an ancestral lineage in the African Great Lakes region
Two exceptional strains of tuberculosis, isolated from East African patients with multi-resistant forms of the disease, have been discovered thanks to the use of a new molecular test, Deeplex-MycTB 1. These strains belong to a so far unknown bacterial lineage, apparently limited to the African Great Lakes region.

Health - 02.06.2020
Promising initial results for a COVID-19 diagnostic test in saliva
Promising initial results for a COVID-19 diagnostic test in saliva
Scientists in the Sys2diag Laboratory (CNRS/ALCEN) and doctors from University Hospital (CHU) of Montpellier have presented the first results of a clinical trial on the EasyCov SARS-CoV-2 detection test. This shows satisfactory performance for a field test that solves a problem in situations where the RT-PCR test cannot be used.
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