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Life Sciences - Health - 23.05.2024
Mechanobiology exerts creative pressure
Mechanobiology exerts creative pressure
Numerous cellular phenomena are guided by mechanical forces, such as embryonic development or the spread of metastases. These phenomena are the subject of intense research aimed at understanding how they are translated into biological processes. Particular emphasis is being placed on new opportunities to treat diseases as resistant as cancer or fibrosis.

Health - 13.05.2024
Breast cancer: a study evaluates the time it takes to return to work
Breast cancer: a study evaluates the time it takes to return to work
After how long do women treated for breast cancer return to work? Until now, there has been little national data on this important aspect of the patient's care. A study carried out by researchers at Claude Bernard Lyon 1 University, Inserm, Gustave Eiffel University and Hospices civils de Lyon, based on data from the Assurance Maladie, has quantified this phenomenon, shedding light on the diversity of situations experienced by these women.

Health - Pharmacology - 13.05.2024
Cancer spread: targeting platelets to counter metastasis?
Scanning electron microscopy. Here we see how platelets (in blue/purple) attach to two tumour cells (in red) in a pre-clinical mouse model. Maria Jesus Garcia Leon (unit 1109 Inserm/Université de Strasbourg) What if our blood platelets , which play a major role in maintaining the integrity of our circulatory system, were not always on our side' Research teams from Inserm, Université de Strasbourg and the French Blood Establishment have studied their role in the process of metastasis formation.

Life Sciences - Health - 07.05.2024
Vulnerability of the placenta to air pollution: what effects on the unborn child’s development?
How does exposure to air pollution affect the proper course of pregnancy and the development of the unborn child' A research team from Inserm and Université Grenoble Alpes investigated the potential effects on placental DNA of exposure to three major airborne pollutants. When comparing the data obtained from around 1 500 pregnant women, it observed that exposure to these pollutants during pregnancy was associated with epigenetic changes liable to alter the development of the foetus, particularly at the metabolic, immune and neurological levels.

Health - Life Sciences - 07.05.2024
Placental vulnerability to air pollution: what effects on the development of the unborn child?
Placental vulnerability to air pollution: what effects on the development of the unborn child?
How does exposure to air pollution during pregnancy affect the pregnancy and the development of the unborn child? A research team from Inserm and Grenoble Alpes University has investigated how placental DNA is modified by exposure to three major air pollutants. By comparing data obtained from almost 1,500 pregnant women, they were able to observe that exposure to these pollutants during pregnancy was associated with epigenetic modifications likely to alter fetal development, particularly at the metabolic, immune and neurological levels.

Health - Life Sciences - 06.05.2024
Discovery of a mechanism that allows Staphylococcus aureus to survive in blood
Staphylococcus aureus (golden staph) is one of the main causes of bacterial infection in France and throughout the world and is particularly responsible for nosocomial infections. Researchers from INRAE, the CEA and CNRS have discovered how this bacterium can survive in the hostile environment of blood.

Health - Agronomy / Food Science - 02.05.2024
Bird flu control for pandemic prevention must start before poultry reach wet markets
Bird flu control for pandemic prevention must start before poultry reach wet markets, new research finds Research published today reveals the speed at which avian influenza ('bird flu') can spread in Asia's live bird markets and the urgent need to pivot pandemic prevention strategies. The paper, from senior scientists in the GCRF One Health Poultry Hub, describes how a computer model of avian influenza virus transmission was for the first time input with biological data obtained from chickens in live bird markets (also known as wet markets).

Health - Environment - 02.05.2024
Modeling avian influenza in Asian poultry markets
A new study involving INRAE reveals the speed at which bird flu is spreading in live poultry markets in Asia. Scientists from the One Health Poultry Hub program have modeled the spread of avian flu in these markets, integrating for the first time biological data collected in the field. They focused their study on the H9N2 avian flu virus, which is not very virulent for poultry, but represents a major risk in the spread and evolution of the disease.

Life Sciences - Health - 24.04.2024
Discovering cancers of epigenetic origin without DNA mutation
Discovering cancers of epigenetic origin without DNA mutation
A research team including scientists from the CNRS 1 has discovered that cancer, one of the leading causes of death worldwide, can be caused entirely by epigenetic changes 2 , in other words, changes that contribute to how gene expression is regulated, and partly explain why, despite an identical genome, an individual develops very different cells (neurons, skin cells, etc.

Health - Agronomy / Food Science - 24.04.2024
The consumption of certain food additive emulsifiers could be associated with the risk of developing type 2 diabetes
The consumption of certain food additive emulsifiers could be associated with the risk of developing type 2 diabetes
Emulsifiers are among the additives most widely used by the food industry, helping to improve the texture of food products and extend their shelf life. Researchers from Inserm, INRAE, Université Sorbonne Paris Nord, Université Paris Cité and Cnam, as part of the Nutritional Epidemiology Research Team (CRESS-EREN), studied the possible links between the dietary intake of food additive emulsifiers and the onset of type 2 diabetes between 2009 and 2023.

Health - Agronomy / Food Science - 23.04.2024
The consumption of certain food additive emulsifiers could be associated with the risk of developing type 2 diabetes
Emulsifiers are among the additives most widely used by the food industry, helping to improve the texture of food products and extend their shelf life. Researchers from Inserm, INRAE, Université Sorbonne Paris Nord, Université Paris Cité and Cnam, as part of the Nutritional Epidemiology Research Team (CRESS-EREN), studied the possible links between the dietary intake of food additive emulsifiers and the onset of type 2 diabetes between 2009 and 2023.

Health - Agronomy / Food Science - 18.04.2024
Displaying the Nutri-Score in advertisements would lead to healthier food choices
Displaying the Nutri-Score in advertisements would lead to healthier food choices
For the first time, a study by a multi-disciplinary team of researchers from Aix-Marseille Université and Sorbonne Paris Nord University, including specialists in the fields of communication, nutrition, epidemiology and public health, has shown that displaying the Nutri-Score on food products in advertisements would lead consumers to choose healthier foods.

Health - Pharmacology - 17.04.2024
Preventing cardiovascular risk thanks to a tool for measuring arterial stiffness
Cardiovascular diseases represent the leading cause of death worldwide . Preventing cardiovascular risk by identifying the people most susceptible to these diseases is a major public health challenge. In a new study in this field, researchers from Inserm, Université de Lorraine and Nancy Regional University Hospital opted to focus on arterial stiffness and how it changes with age, given that ageing is associated with a loss of arterial flexibility.

Life Sciences - Health - 14.04.2024
Muting tinnitus
Research on tinnitus, a recent investigative field, is now enabling a clearer understanding of the causes and effects of this symptom that affects nearly eight million people in France. Buzzing, hissing, creaking, ringing, clicking or humming; according to a recent French study, although 23 million French people over the age of 15 have experienced tinnitus once in their lives, between four and seven million of them suffer from it on a permanent basis.

Health - Pharmacology - 10.04.2024
Respiratory allergies: newly discovered molecule plays a major role in triggering inflammation
Respiratory allergies: newly discovered molecule plays a major role in triggering inflammation
Inflammation plays a major role in allergic diseases, affecting at least 17 million people in France, including 4 million asthmatics. One of the molecules that initiates this process in the respiratory tract has just been identified. This molecule, a member of the alarmin family, is a major therapeutic target for the development of new treatments for respiratory allergies.

Chemistry - Health - 21.03.2024
First Complete Vascularization of Organoids on Microfluidic Chip
First Complete Vascularization of Organoids on Microfluidic Chip
In Vitro System Bypasses -Complex Technical Setups- of Alternative Approaches And Supports Production Scaling e Interdisciplinary Research Institute of Grenoble (IRIG) , CEA-Leti and fellow European and Canadian institutes and researchers have demonstrated the complete vascularization of organoids on a microfluidic chip at speeds and flow rates similar to blood's, improving functional maturation and enabling their long-term survival.

Chemistry - Health - 21.03.2024
International Research Team Achieves First-Reported, Complete Vascularization of Organoids on Microfluidic Chip
In Vitro System Bypasses -Complex Technical Setups- of Alternative Approaches And Supports Production Scaling e Interdisciplinary Research Institute of Grenoble (IRIG) , CEA-Leti and fellow European and Canadian institutes and researchers have demonstrated the complete vascularization of organoids on a microfluidic chip at speeds and flow rates similar to blood's, improving functional maturation and enabling their long-term survival.

Health - 20.03.2024
A study on the pre-COVID-19 health of French citizens to help decision-makers reduce the disease burden
A study on the pre-COVID-19 health of French citizens to help decision-makers reduce the disease burden
In order to implement suitable public health policies, it is crucial to know the health status of the population and its evolution over time. This knowledge is all the more important given the severe disruptions caused by the COVID-19 pandemic to healthcare systems worldwide.

Life Sciences - Health - 14.03.2024
Amyotrophic lateral sclerosis: a new avenue for improving patient diagnosis and follow-up
Amyotrophic lateral sclerosis: a new avenue for improving patient diagnosis and follow-up
Amyotrophic lateral sclerosis or Charcot's disease is a neurodegenerative disease that results in progressive paralysis and subsequent death. Diagnosing it is difficult and no curative treatment exists to date, making these challenges for research. In a new study, Inserm researcher Caroline Rouaux and her team at the Strasbourg Biomedical Research Centre (Inserm-Université de Strasbourg), in collaboration with researchers from Ludwig Maximilian University in Munich, CNRS and Sorbonne Université, show that electroencephalography could become a diagnostic and prognostic tool for the disease.

Health - Pharmacology - 11.03.2024
A promising vaccine against Nipah virus infection
A promising vaccine against Nipah virus infection
The WHO recently classified the Nipah virus (NiV) as one of the eight main emerging pathogens likely to cause major epidemics in the future. In a context where no treatment or vaccine is yet available, a team comprising researchers from Inserm (Unit 955-VRI) and from the Université Paris-Est Créteil (UPEC) is presenting the preclinical results of an innovative vaccine against this virus.
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