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Health - 07.10.2016
Rituximab effective in the treatment of membranous glomerulonephritis
A national trial on membranous glomerulonephritis in 80 patients was coordinated by Prof. Pierre Ronco, of the Department of Nephrology and Dialysis at Tenon Hospital AP-HP, of the Inserm Unit 'Rare and common kidney diseases, matrix remodelling and tissue repair' and Pierre and Marie Curie University, and by Dr Karine Dahan, of the Nephrology Day Hospital at Tenon Hospital AP-HP.

Health - 06.10.2016
New immunotherapy-based approach for post-transplant leukaemia relapse
An Inserm team from the Mondor Institute for Biomedical Research (IMRB) has just identified a key switch in the immune response, and proposes a new immunotherapy-based approach for combating leukaemia. And maybe other cancers in time. This work is published in the journal Blood . Towards a new immunotherapy for cancer?

Life Sciences - Health - 05.10.2016
Eating well to grow well: discovery of a missing link
Rénald Delanoue, Inserm Researcher, and his colleagues at the Institute of Biology Valrose in Nice (Inserm-CNRS-Université Côte d'Azur) have identified the missing links in the process that regulates the size of an organism based on the richness of its diet. Their research was conducted on Drosophila , an insect that seems very distant from humans, but the study of which has nonetheless enabled many advances in biomedical research.

Life Sciences - Health - 04.10.2016
Invasive insects: an underestimated cost to the world economy
Invasive insects: an underestimated cost to the world economy
Invasive insects cause at least 69 billion euros of damage per annum worldwide.

Life Sciences - Health - 12.09.2016
Low birth rate after cloning: the consequences of highly disruptive interactions between uterus and embryo
Low birth rate after cloning: the consequences of highly disruptive interactions between uterus and embryo
When comparing cloned animal embryos and embryos that come about as a result of artificial insemination, there is a difference in gene expression at the moment implantation occurs in the uterus for more than 5 000 genes. Researchers at INRA and the University of California are shining the spotlight on this critical step for the survival of cloned embryos in cattle.

Life Sciences - Health - 12.09.2016
Low birth rate after cloning: the consequences of highly disruptive interactions between uterus and embryo
Low birth rate after cloning: the consequences of highly disruptive interactions between uterus and embryo
When comparing cloned animal embryos and embryos that come about as a result of artificial insemination, there is a difference in gene expression at the moment implantation occurs in the uterus for more than 5 000 genes. Researchers at INRA and the University of California are shining the spotlight on this critical step for the survival of cloned embryos in cattle.

Life Sciences - Health - 02.09.2016
Placenta in females, muscle mass in males: the dual heritage of a virus
Placenta in females, muscle mass in males: the dual heritage of a virus
It was already known that genes inherited from ancient retroviruses 1 are essential to the placenta in mammals, a finding to which scientists in the Laboratoire Physiologie et Pathologie Moléculaires des Rétrovirus Endogènes et Infectieux (CNRS/Université Paris-Sud) contributed. Today, the same scientists 2 have revealed a new chapter in this astonishing story: these genes of viral origin may also be responsible for the more developed muscle mass seen in males! Their findings are published on 2 September 2016 in PLOS Genetics .

Life Sciences - Health - 30.08.2016
Caffeine reverts memory deficits
Caffeine reverts memory deficits
The mechanism by which caffeine counteracts age-related cognitive deficits in animals has been revealed. The study coordinated by Portuguese researchers from Instituto de Medicina Molecular (iMM Lisboa) and collaborators from Inserm in Lille, France, along with teams from Germany and United States, showed that the abnormal expression of a particular receptor - the adenosine A2A, target for caffeine - in the brain of rats induces an aging-like profile namely memory impairments linked to the loss of stress controlling mechanisms.

Health - Life Sciences - 05.08.2016
Malaria and toxoplasmosis have an Achilles heel from plants
Malaria and toxoplasmosis have an Achilles heel from plants
To survive, the parasites responsible for malaria and toxoplasmosis depend on mechanisms inherited from the plant world. This is what a team of researchers from CNRS 1 (Institute for Advanced Biosciences, CNRS/INSERM/Université Grenoble Alpes) and the University of Melbourne 2 has shown. They have just published two studies in Cell Microbiology and PLOS Pathogens.

Life Sciences - Health - 03.08.2016
The keys to a major process in DNA repair
Researchers from the Institut Jacques Monod (CNRS/University of Paris Diderot), the Institute of Biology of the Ecole Normale Supérieure (ENS/CNRS/Inserm), and the University of Bristol, have described for the first time in its totality the mechanisms by which DNA damaged by UV radiation is repaired, and how the proteins involved in this process cooperate to ensure its efficiency.

Life Sciences - Health - 29.07.2016
A virtual brain helps decrypt epilepsy
Researchers at CNRS, INSERM, Aix-Marseille University and AP-HM have just created a virtual brain that can reconstitute the brain of a person affected by epilepsy for the first time. From this work we understand better how the disease works and can also better prepare for surgery. These results are published in Neuroimage, on July 28, 2016.

Health - Life Sciences - 29.07.2016
A virtual brain helps decrypt epilepsy
A virtual brain helps decrypt epilepsy
Researchers at CNRS, INSERM, Aix-Marseille University and AP-HM have just created a virtual brain that can reconstitute the brain of a person affected by epilepsy for the first time. From this work we understand better how the disease works and can also better prepare for surgery. These results are published in Neuroimage, on July 28, 2016.

Health - Administration - 27.07.2016
Inserm, France’s rising research star according to Nature
The French National Institute of Health and Medical Research (Inserm) is the only research institution in France listed in the World Top 100 institutions with the most progress in the last 3 years.

Life Sciences - Health - 21.07.2016
Long term correction of hyperbilirubinemia in animal models of Crigler-Najjar syndrome
Dr. Federico MINGOZZI, Team Leader of the Immunology and Liver Gene Transfer unit at Généthon, (Inserm U951/UPMC), France, has demonstrated the long-term efficacy of an optimized AAV-UGT1A1 ve

Health - Life Sciences - 20.07.2016
An antibody-based drug for multiple sclerosis
Inserm Unit U919, directed by Prof. Denis Vivien ('Serine Proteases and Physiopathology of the Neurovascular Unit') has developed an antibody with potential therapeutic effects against multiple sclerosis.

Health - 06.07.2016
Very premature infants: towards better care
Born too soon, very premature infants are particularly vulnerable and need appropriate care. The European project EPICE (Effective Perinatal Intensive Care in Europe) examines how medical practices based on scientific evidence are incorporated into the care of these neonates . The study, coordinated by Inserm and published in The British Medical Journal , highlights the underuse of four effective practices for improving their survival and long-term health, and estimates its impact on mortality and morbidity.

Health - 01.07.2016
Frigate birds : never touching down
Frigate birds : never touching down
Frigate birds were already known for their ability to fly continuously for weeks without landing. A telemetric study of their trajectory and flight strategy has just revealed that they can remain airborne for over two months during their transoceanic migrations.

Philosophy - Health - 30.06.2016
Ethical issues surrounding CRISPR-Cas9 technology
Font size Bookmark Print Tip a friend On 13 June last, the Inserm Ethics Committee assembled over a hundred individuals at its annual seminar. All those present had the benefit of an ethical perspective on many problems posed by biomedical research. One of the questions addressed was that of CRISPR-Cas9 technology.

Life Sciences - Health - 17.06.2016
A novel research program on traumatic memories
How will the traumatic events of the terrorist attacks of 13 November 2015 evolve in people's memories, whether collective or individual?

Health - 26.05.2016
Targeting metals to fight Staphylococcus aureus
Researchers from CEA, CNRS, Aix-Marseille Université and INRA, in France have discovered a unique system of acquisition of essential metals in the pathogenic bacterium Staphylococcus aureus.
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