Thomas Vosegaard, Visiting Professor at CRMN

Professor of Biological NMR Spectroscopy, Director of the Interdisciplinary Nanoscience Center and of the Department of Chemistry at Aarhus University
Visiting Professor 2022-2023 - from 1 to 30 of April, 2023
Inviting Professor: Anne Lesage and Guido Pintacuda

Biography

Professor Thomas VOSEGAARD is currently Director of the Interdisciplinary Nanoscience Centre and the Department of Chemistry at Aarhus University; he is also Professor of Biology NMR Spectroscopy. He continued his studies in chemistry at the university, where he is now a professor, until he obtained his PhD, for which he received a PhD Prize from the Danish Natural Science Academy. He is particularly interested in the development and application of NMR spectroscopy to the study of the molecular structure and dynamics of biological systems, lipidomics, the automation of NMR processes and analyses, advanced numerical simulations for NMR in the solid and liquid states, and the development of new teaching activities based on information technologies.

Collaboration with CRMN

His visit to the CRMN laboratory is the result of an ongoing collaboration between Aarhus University and the CRMN. The challenge of this collaboration is to couple computational tools with the use of CRMN’s unique experimental resources, which will be decisive in extending the scope of solid-state NMR spectroscopy to the chemical community. These areas of application are of indisputable interest and have a very strong global impact. Pr. T. Vosegaard has developed one of the major platforms for solid-state NMR simulations (SIMPSON, +500 users), which represents the ideal start for extending the software to a comprehensive simulation platform as described above. This project marries strategically well with the activity of the CRMN in Lyon, substantially improving the quality and quantity of the service offered. Within the visit, we will benchmark the first ideas and routines developed so far with data acquired at the CRMN on exciting classes of samples, and plan to lay foundations for future collaborations. The visit will give ample opportunity for discussions and the development of new ideas. By joining forces, we will be able to push the frontline of this new research area forward quickly. Additionally, Prof. Vosegaard will take part in the undergraduate teaching, targeting M1, M2 and PhD students with a series of lectures on solid-state NMR and more specifically on the quantum mechanics behind the magnetic resonance phenomena, on the NMR properties of quadrupolar nuclei and on the computational tools available for simulating and interpreting experimental NMR data.

Major publications

  • T. M. Ho, F. Abik, S. Hietala, E. Isaza Ferro, L. Pikänen, D. W. Juhl, T. Vosegaard, P. O. Kilpeläinen, and K. S. Mikkonen. Cellulose 30, 753 (2023). Wood lignocellulosic stabilizers: effect of their characteristics on stability and rheological properties of emulsions
  • T. Sandfeld, K. G. Malmos, C. B. Nielsen, M. B. Thomsen, J. Bechsgaard, M. Wurster, M. Lalk, M. Johannsen, T. Vosegaard, T. Bilde, and A. Schramm. Front. Ecol. Evol. 10, 841490 (2022). Metabolite profiling of the social spider Stegodyphus dumicola along a climate gradient
  • T. Vosegaard. Progr. Nucl. Magn. Reson. Spectrosc. 123, 51 (2021). Single-crystal NMR Spectroscopy
  • K. G. Malmos, A. H. Lüdeking, T. Vosegaard, A. Aagaard, J. Bechsgaard, J. G. Sørensen, and T. Bilde. Func. Ecol. 35, 2728 (2021). Behavioural and physiological responses to thermal stress in a social spider
  • S. Fruergaard, M. B. Lund, A. Schramm, T. Vosegaard, and T. Bilde. iScience 24, 103125 (2021). The myth of antibiotic spider silk.