news 2025

A study by Inserm, in collaboration with the CNRS, the University of Grenoble Alpes (UGA), the Grenoble Alpes University Hospital (CHU), and the Barcelona Institute for Global Health (ISGlobal), published on December 9 in the The Lancet Planetary Health journal, suggests there may be an association between exposure in the third trimester of pregnancy to two synthetic phenols, methylparaben and bisphenol S, commonly found in everyday products (food, cosmetics, plastics, etc.), and questionnaire scores that could suggest behavioral disorders in children.

The presence of a compound present in cruciferous vegetables, indole-3-carbinol, is essential to make certain cancer treatments effective. Photo by Monika Borys / Unsplash It is a universally recognized truth that vegetables are good for your health. A study conducted by Institut Curie and Inserm reveals that the presence of a compound present in cruciferous vegetables, indole-3-carbinol, is essential to make certain cancer treatments effective.

Two researchers from Inserm and one researcher from INRAE contributed to a series of three articles published on 19 November in The Lancet on the health consequences of consuming ultra-processed foods. The 43 international scientists who signed this series of articles propose the implementation of public health measures to limit the use of ultra-processed foods and improve nutrition worldwide.

According to a communication from the CNRS dated November 12, 2025. Based on a scientific publication in Nature Ecology & Evolution to which Lucie Étienne, CNRS research director at CIRI, and Alexandre Legrand, INSERM researcher and CIRI doctor, contributed: Evolutionary characterization of antiviral SAMD9/9L across kingdoms supports ancient convergence and lineage-specific adaptations.

A cellular resistance mechanism at the origin of relapses of triple-negative breast cancer has recently been discovered by scientists from CNRS, Institut Curie and Université Paris Cité. Their findings have been published in Cancer Research, a journal of the American Association for Cancer Research, on 6 November 2025.

4D visualisation of the vascularisation of an entire kidney obtained using the multi-lens probe developed in this study. Veins are shown in blue and arteries in red. Colour variations indicate blood flow velocity: the brighter the colour, the faster the blood is flowing. The smallest vessels are less than 100 micrometres in diameter.

Consumption of plant-based products is associated with better cardiovascular health, provided they are of good nutritional quality and not or minimally processed. This is the finding of a research team from INRAE, Inserm, Sorbonne Paris Nord University and Cnam, based on analysis of health data from a cohort of 63,835 adults.

Molecules passing through the colon epithelium via specialized pathways (goblet cells). In red: the molecules transported (antigens); in blue: the epithelium. Institut Pasteur/Microbiome-Host Interactions/Clara Delaroque and Benoit Chassaing A study conducted in mice by scientists from the Institut Pasteur and Inserm reveals that maternal consumption of dietary emulsifiers can have a negative impact on the gut microbiota of their offspring.

Women suffering from long COVID have a greater risk 1 of experiencing abnormal uterine bleeding 2 . The symptoms of the illness intensify during the perimenstrual and proliferative phases of the menstrual cycle, notably fatigue, headaches, and muscle pain. This bidirectional relationship between long COVID and menstrual disorders has been revealed by a French-British research team co-led by a CNRS researcher 3 .

Mouse skin structure after stretching, using histological staining. The scale bar corresponds to 100 micrometers. Darawan Tabtim-On and Renaud Leclère - Experimental Pathology Platform, Institut Curie What if vaccination could be administered by simple skin application rather than injection? A team of researchers from Inserm, Institut Curie, and King's College London investigated the impact of external mechanical constraints (skin stretching, friction, etc.) on skin impermeability in animals and humans.

With neonatal mortality on the increase in France, a new study by Inserm, Paris Cité University, Inrae, Paris Nord University and APHP, published on 16 September in BMJ Medicine , shows that it could be linked to socioeconomic inequalities. Using their social deprivation index adjusted for the perinatal period, the researchers observed that the risk of neonatal death is higher for mothers living in deprived municipalities.

In ICARUS-BREAST 01 study, more than half of the patients with metastatic breast cancer saw their disease reduce or disappear completely thanks to the treatment. In some cases, this response has now lasted for more than two years. Dr Barbara Pistilli, Head of the Breast Cancer Group at Gustave Roussy and Guillaume Montagnac, Inserm researcher, Head of Tumor Cell Dynamics unit, coordinated the study, the results of which have just been published in Nature Medicine.

In the ICARUS-BREAST 01 study, more than half of patients with metastatic breast cancer experienced a reduction or complete disappearance of their disease thanks to treatment, and in some patients, this response has now lasted for more than two years. Dr Barbara Pistilli, Head of the Breast Pathology Committee at Gustave Roussy, and Guillaume Montagnac, an Inserm researcher in the "Tumor Cell Dynamics" unit he heads at Gustave Roussy, are please

Until October 12, 2025, the Prieuré Saint-Cosme - Demeure de Ronsard presents "Soigner corps et âmes en Touraine", an exhibition organized by the Conseil départemental d'Indre-et-Loire, with the support of Inrap.

What if the study of bacteria could illuminate our understanding of human immunity? In recent years, scientists have been exploring unexpected links between human proteins involved in the body's defense mechanisms and certain bacterial immune proteins. Focusing on conserved immune domains originating from bacteria, termed "ancestral immune", a team of researchers from Institut Curie, Institut Pasteur, and Inserm identified a novel human immune protein, SIRal.

In people living with obesity, visceral adipose tissue - located deep around the organs - can become fibrous and rigid. This phenomenon, known as fibrosis , disrupts normal fat function and contributes to metabolic complications such as insulin resistance and type 2 diabetes. A team of researchers from Sorbonne University, Inserm and AP-HP, working in the Nutriomics laboratory, has identified a new therapeutic strategy to counter the effects of fibrosis.

Llamas possess a particular type of antibody that scientists have just used to produce mini antibodies. These "nanobodies" easily pass through the biological barrier that protects brain cells 1 , making them more effective than the antibodies currently used in treatments. Biodegradable and associated with limited secondary effects, today they promise a new generation of treatments for schizophrenia.

A team from the Institut Curie, Inserm and CNRS has uncovered a hitherto unknown molecular mechanism linking estrogens (female sex hormones) to the aggravation of certain cancers not traditionally considered hormone-dependent, such as melanoma, gastric cancer and thyroid cancer.minine sex hormones) to the aggravation of certain cancers not traditionally considered hormone-dependent, such as melanoma, gastric cancer and thyroid cancer.

A new class of molecules capable of killing the cancer cells that are refractory to standard treatments and responsible for recurrence has just been developed by scientists at Institut Curie, the CNRS, and Inserm. This crucial advance in the fight against metastatic cancer is based on identifying the cellular site for ferroptosis initiation, a natural process, catalysed by iron, that sparks the oxidative degradation of cell membranes.

Characteristic depressive episodes are the most common mental disorders worldwide. One in five people will suffer from depression in their lifetime, with suicidal risk responsible for several thousand deaths a year in France.